Glutamatergic and GABAergic metabolite levels in schizophrenia-spectrum disorders: a meta-analysis of 1H-magnetic resonance spectroscopy studies

T Nakahara, S Tsugawa, Y Noda, F Ueno… - Molecular …, 2022 - nature.com
… Thus, simultaneous measurement of Glu and GABA levels in the brain could lead to a …
GABA levels in the brains of the patient group and HC using 1 H-MRS; (3) acquired Glu or GABA

In vivo brain glutathione is higher in older age and correlates with mobility

KE Hupfeld, HW Hyatt, P Alvarez Jerez… - Cerebral …, 2021 - academic.oup.com
… and two edited MRS scans to quantify neurometabolites in a frontal and sensorimotor voxel.
… as the outcome variable and GSH, Glx, and GABA as predictors, controlling for the above …

Age and sex influences gamma-aminobutyric acid concentrations in the developing brain of very premature infants

SK Basu, S Pradhan, MB Jacobs, M Said, K Kapse… - Scientific Reports, 2020 - nature.com
… -PRESS spectra to simultaneously characterize the temporal … pulses of 16 ms duration were
used as editing pulses in our … 6 metabolites: GABA, glutamine, glutamate, glutathione, NAA …

Distribution Pattern of Closed and Extended Forms of Glutathione in the Human Brain: MR Spectroscopic Study

PK Mandal, R Guha Roy, A Kalyani - ACS Chemical Neuroscience, 2023 - ACS Publications
… those found in in vivo MRS studies and found an excellent … of other neurochemicals like
GABA and NAA has been … amount of ROS and free radicals simultaneously. In the presence of …

Metabolic profile of complete spinal cord injury in pons and cerebellum: A 3T 1H MRS study

JK Richter, V Vallesi, N Zölch, KL Chan, N Hunkeler… - Scientific reports, 2023 - nature.com
… In a recently published study, we showed that the levels of glutathione (GSH) in the pons (acquired
with standard point-resolved spatially localized spectroscopy (PRESS) sequence) …

Evaluating Back-to-Back and Day-to-Day Reproducibility of Cortical GABA+ Measurements Using Proton Magnetic Resonance Spectroscopy (1H MRS)

S Elsaid, P Truong, N Sailasuta, B Le Foll - International Journal of …, 2023 - mdpi.com
… glutamate and glutathione, GABA is linked to metabolic pathways in the brain [1,2]. GABA is
… Given that the GABA-edited peak is contaminated with MM, we refer to the measurement of …

γ‐aminobutyric acid measurement in the human brain at 7 T: Short echo‐time or Mescher–Garwood editing

SI Lim, L Xin - NMR in Biomedicine, 2022 - Wiley Online Library
… However, the GABA editing efficiency at a TE of 80 ms increased by 3.0% relative to that at
… profile simultaneously. In areas of low GABA concentration, the editing method is a more …

Local and interregional neurochemical associations measured by magnetic resonance spectroscopy for studying brain functions and psychiatric disorders

J Shen, D Shenkar, L An, JS Tomar - Frontiers in Psychiatry, 2020 - frontiersin.org
… as GABA, N-acetylaspartylglutamate (NAAG), and glutathione … , it is not surprising that the
proton MRS has found abnormal … (marked by an arrow) simultaneously reduced fitted NAA and …

Determination of Brain Metabolite T1 Without Interference From Macromolecule Relaxation

L An, MF Araneta, M Victorino… - Journal of Magnetic …, 2020 - Wiley Online Library
editing technique 15 simultaneously measured glutamate (Glu), glutamine (Gln), γ-aminobutyric
acid (GABA), and glutathione (GSH) … MRS data were collected using the proposed pulse …

[HTML][HTML] Comparison of methods for spectral alignment and signal modelling of GABA-edited MR spectroscopy data

R Rideaux, M Mikkelsen, RAE Edden - Neuroimage, 2021 - Elsevier
… Here we use the proportion of grey matter within the MRS voxel as a proxy for ground-truth
GABA concentration to compare the performance of four spectral alignment methods (ie, …