… Regulatory T (Treg) and Th17 cells are critical Th cell types … responses, TGF-β1 mainly
targets T cells because T-cell-specific … region to reduce inhibitory histone markers of H3K27me3 […

… , and IFI44L and decreased expression of CD69 and CD25. C4 was distinguished … FOXP3
is a transcriptional regulator of conventional CD4 + Tregs and is often coexpressed with CD25 …

… CD69 with about half co-expressing CD103 (Supplementary … We hypothesized that reduced
T RM cell numbers in Foxp3 … reg cells, which do not show differential expression for TGF-β1 …

… not shown), FOXP3 was coexpressed with CTLA4 and IL2RA… , including Tregs, are the
sources of TGFβ1 within the tissue. … a 40-μmol/L mesh to obtain single cells. Up to 1 × 10 7 …

… CD25 + TregP cells show higher rates of apoptosis and … CD25 + TregP cells and Foxp3 lo
TregP cells originate by acquiring … and survival and leads to decreased expression of genes …

… cells (Thelper) and regulatory T cells (Treg) for CD4 + T cells … Strikingly, this CD4 + FoxP3
+ CD25 hi Treg cluster … expressing Ki-67 + CD25 + and co-expressing ICPs correlated with …

… C5–CD4, which was finally identified as regulatory CD4+ T … study, including marker genes
(FOXP3 and IL2RA), costimulatory … classical PC subcluster coexpressed marker genes CD138 …

… -β when αvβ8 expressed by one cell binds to cell-surface L–… cells participated in the local
conversion of CD25 + FOXP3 − … –TGF-β1 or mutant incapable of producing diffusible TGF-β1 […

… CD4 T cells in the presence of recombinant human TGF-β1 [… CD8A, CD4, FOXP3, IL2RA
and MKI67. Cytotoxic CD4conv T … co-expressing Th1, Th17 and cytotoxic gene programs are …

… By integrating single cell TCRseq/RNAseq from human NSCLC … We next queried the murine
single-cell data for coexpression of … To determine whether the decreased FoxP3 mRNA was …