[HTML][HTML] The A328 V/E (rs2887147) polymorphisms in human tryptophan hydroxylase 2 compromise enzyme activity
N Carkaci-Salli, MC Bewley, I Tekin… - … and Biophysics Reports, 2023 - Elsevier
… naturally-occurring single nucleotide polymorphisms (SNPs) … Until 2003, it was thought that
only one isoform of TPH existed… novel mechanistic insight. In vivo, at low concentrations of …
only one isoform of TPH existed… novel mechanistic insight. In vivo, at low concentrations of …
Genetic variants and haplotypes of tryptophan hydroxylase 2 and reelin genes may be linked with attention deficit hyperactivity disorder in Egyptian children
WMM Abo El Fotoh, NR Bayomy… - ACS Chemical …, 2020 - ACS Publications
… analyze the haplotype frequencies of these four SNPs instead of considering separate genes.
Three of the four single nucleotide polymorphisms under study … GTAC haplotypes were …
Three of the four single nucleotide polymorphisms under study … GTAC haplotypes were …
Association between lifelong premature ejaculation and polymorphism of tryptophan hydroxylase 2 gene in the Han population
X Fu, X Zhang, T Jiang, Y Huang, P Cheng… - Sexual …, 2020 - academic.oup.com
… polymorphisms may be theoretically associated with the occurrence and development of LPE,
which could potentially become a novel … database of single nucleotide polymorphism 147, …
which could potentially become a novel … database of single nucleotide polymorphism 147, …
Relationships of Ischemic Stroke Occurrence and Outcome with Gene Variants Encoding Enzymes of Tryptophan Metabolism
… presence of a specific single nucleotide polymorphism (SNP) have … Haplotype analysis of
the identified LD blocks revealed no … Tryptophan hydroxylase (TPH1) is a protein of 444 amino …
the identified LD blocks revealed no … Tryptophan hydroxylase (TPH1) is a protein of 444 amino …
The relationship of tryptophan hydroxylase-2 methylation to early-life stress and its impact on short-term antidepressant treatment response
T Shen, X Li, L Chen, Z Chen, T Tan, T Hua… - Journal of Affective …, 2020 - Elsevier
… According to our previous studies, single nucleotide polymorphisms (SNPs) of TPH2 (… to
novel strategies in developing more precise psychotherapeutic agents for MDD. Our study offers …
novel strategies in developing more precise psychotherapeutic agents for MDD. Our study offers …
Investigation of polymorphic variants of SLC6A4 TPH-1, and TPH-2 genes in cases of completed suicide
D Kilicaslan, O Cumaogullari, E Emiral… - JOURNAL OF MENS …, 2022 - avesis.ankara.edu.tr
… isoform (TPH2) gene provide evidence for association with major depression. … Single
nucleotide polymorphism and haplotype analysis of a novel tryptophan hydroxylase isoform (TPH2) …
nucleotide polymorphism and haplotype analysis of a novel tryptophan hydroxylase isoform (TPH2) …
Association of TPH1 and TPH2 Gene Polymorphisms with the Risk of Developing Psychoneurological Disorders
PV Moskaleva, NA Shnayder, DV Dmitrenko… - Neuroscience and …, 2022 - Springer
… of a series of single-nucleotide polymorphisms (SNP) in the … phan hydroxylase isoforms –
tryptophan hydroxylase 1 and … However, haplotype analysis revealed an increase in the risk …
tryptophan hydroxylase 1 and … However, haplotype analysis revealed an increase in the risk …
A regulatory variant of tryptophan hydroxylase gene modulates transcription activity and biases growth rate in the Pacific oyster, Crassostrea gigas
… and haplotype analysis of single nucleotide polymorphisms (… , −262 bp) and two haplotypes
(CCCC and TCTC) that were … Together, we identified a novel SNP in the regulatory region …
(CCCC and TCTC) that were … Together, we identified a novel SNP in the regulatory region …
Identifying patients with major depressive disorder based on tryptophan hydroxylase-2 methylation using machine learning algorithms
R Fan, T Hua, T Shen, Z Jiao, Q Yue, B Chen, Z Xu - Psychiatry research, 2021 - Elsevier
… the positive association between two single nucleotide polymorphisms (SNPs) of TPH2 (…
This study aimed to provide a novel modeling method, ML algorithms, for identifying patient …
This study aimed to provide a novel modeling method, ML algorithms, for identifying patient …
Genetic Variants Associated with Aggressive Behaviour in Humans: The Serotonergic System
PG Mariana de Leão - 2020 - search.proquest.com
… Tryptophan Hydroxylase. This protein is responsible for the first, rate-limiting step in serotonin
synthesis, catalysing the aminoacid LTryptophan … the four possible haplotypes. While some …
synthesis, catalysing the aminoacid LTryptophan … the four possible haplotypes. While some …