Single-cell analysis of human retina identifies evolutionarily conserved and species-specific mechanisms controlling development
… RNA sequencing (scRNA-seq) has allowed high-resolution analysis of … identify the
transcriptional networks governing human retinal development, we performed scRNA-seq analysis …
transcriptional networks governing human retinal development, we performed scRNA-seq analysis …
[HTML][HTML] A single-cell guide to retinal development: Cell fate decisions of multipotent retinal progenitors in scRNA-seq
… landscape governing organ development. Here, we review the application of single-cell
profiling techniques to the developing vertebrate retina, including early studies identifying …
profiling techniques to the developing vertebrate retina, including early studies identifying …
Gene regulatory networks controlling temporal patterning, neurogenesis, and cell-fate specification in mammalian retina
… In this study, we use integrated single-cell RNA and single-cell ATAC sequencing (scATAC-…
Single-cell RNA-seq analysis of retinal development identifies NFI factors as regulating …
Single-cell RNA-seq analysis of retinal development identifies NFI factors as regulating …
Robust reprogramming of glia into neurons by inhibition of Notch signaling and NFI factors in adult mammalian retina
… regulatory network that restores Müller glia to a resting state 6. Within this network, we identified
the Nuclear Factor I (NFI) … lineage analysis, immunohistochemistry, and single-cell RNA- …
the Nuclear Factor I (NFI) … lineage analysis, immunohistochemistry, and single-cell RNA- …
Gene regulatory networks controlling vertebrate retinal regeneration
… also conducted single-cell RNA-seq (scRNA-seq) to identify … well as after treatment with
exogenous factors that induced injury-… regulatory network that includes NFI factors, which are up-…
exogenous factors that induced injury-… regulatory network that includes NFI factors, which are up-…
Nuclear Factor I in neurons, glia and during the formation of Müller glia‐derived progenitor cells in avian, porcine and primate retinas
HM El‐Hodiri, WA Campbell, LE Kelly… - Journal of …, 2022 - Wiley Online Library
… Chick single-cell RNAseq (scRNAseq) data are shared as … This study demonstrates that
NFI transcription factors are … RNA-Seq data for gene-cell matrices are deposited in GitHub …
NFI transcription factors are … RNA-Seq data for gene-cell matrices are deposited in GitHub …
Single‐cell RNA sequencing: A new opportunity for retinal research
M You, R Rong, Z Zeng, H Li, X Xia… - Wiley Interdisciplinary …, 2021 - Wiley Online Library
… The mechanism by which NFI transcription factors regulate the … Moreover, it has identified
genes and transcription factors … Peng et al. used 165,000 single-cell RNA-seq profiles to …
genes and transcription factors … Peng et al. used 165,000 single-cell RNA-seq profiles to …
[PDF][PDF] Robust reprogramming of glia into neurons by inhibition of Notch signaling and NFI factors in adult
… regulatory network that restores Müller glia to a resting state 6. Within this network, we identified
the Nuclear Factor I (NFI) … lineage analysis, immunohistochemistry, and single-cell RNA- …
the Nuclear Factor I (NFI) … lineage analysis, immunohistochemistry, and single-cell RNA- …
Single-cell analyses reveal transient retinal progenitor cells in the ciliary margin of developing human retina
B Dorgau, J Collin, A Rozanska, D Zerti… - Nature …, 2024 - nature.com
… In retinal progenitor cells, we identified a significant enrichment … Enrichment of NFI binding
motif family members was observed … Using spatiotemporal single cell RNA-Seq analyses we …
motif family members was observed … Using spatiotemporal single cell RNA-Seq analyses we …
Single cell transcriptomics reveals lineage trajectory of retinal ganglion cells in wild-type and Atoh7-null retinas
… Here we report our further study of the roles of these transcription factors. Using bulk RNA-seq,
we identify genes regulated by the three transcription factors, which expand our …
we identify genes regulated by the three transcription factors, which expand our …