… for size, surface charge, polymer degradation, co‐delivery, and manufacturability in the development of polymeric particle vaccines for infectious diseases

CJ Genito, CJ Batty, EM Bachelder… - Advanced …, 2021 - Wiley Online Library
… If a range of sizes are reported in the publication, then the smallest size is presented. Sizes
of … for the design of vaccine delivery systems, as an optimal degradation rate may exist for …

Inhalable dry powder mRNA vaccines based on extracellular vesicles

KD Popowski, A Moatti, G Scull, D Silkstone, H Lutz… - Matter, 2022 - cell.com
… can serve as an inhaled mRNA drug-delivery system that is superior to synthetic liposomes.
… and Drug Administration. However, formulating drugs and vaccines for inhaled delivery may …

Nanoparticles as adjuvants in vaccine delivery

A Garg, HK Dewangan - … in Therapeutic Drug Carrier Systems, 2020 - dl.begellhouse.com
… with a length of 100 to 1000 nm, whereas MSNs have size in … water-in-oil systems with a
droplet size ranging from 50 to 600 … Particles with a diameter less than 500 nm are optimal for …

Current progress in particle-based systems for transdermal vaccine delivery

J Pielenhofer, J Sohl, M Windbergs… - Frontiers in …, 2020 - frontiersin.org
… depends on the size of the particles, with an optimum of ~… in nano-sized droplets with droplet
sizes of <500 nm into the … modification of vaccines, including the small droplet size, high …

Microneedles: a new generation vaccine delivery system

I Menon, P Bagwe, KB Gomes, L Bajaj, R Gala… - Micromachines, 2021 - mdpi.com
… 50 to 900 μm in length can efficiently deliver the vaccine to the … to the innate immune system
leading to optimal adaptive immune … ’ smaller size allows for precise delivery into the dermal …

The 3Ds in virus‐like particle based‐vaccines: “Design, Delivery and Dynamics

MO Mohsen, G Augusto… - Immunological reviews, 2020 - Wiley Online Library
… Adjusting size and zeta potential may allow investigators to … smoking 48 and a vaccine
displaying full-length interleukin (IL)-1β … However, the science of vaccine administration route is a …

Vaccine delivery systems toward lymph nodes

Y Ding, Z Li, A Jaklenec, Q Hu - Advanced drug delivery reviews, 2021 - Elsevier
… A huge difference in the sizes of existing vaccine antigens, … The optimal size of vaccine
systems is largely decided by the … The optimized size of the vaccine delivery system allowed it …

[HTML][HTML] The impact of size on particle drainage dynamics and antibody response

S Zinkhan, A Ogrina, I Balke, G Reseviča… - Journal of controlled …, 2021 - Elsevier
Vaccine-induced immune response can be greatly enhanced … The size of the CCMV TT
-Ctt-SS greatly varies in length but … VLPs of a size smaller than 200 nm are optimal for induction …

The sixth revolution in pediatric vaccinology: immunoengineering and delivery systems

D Soni, S Bobbala, S Li, EA Scott, DJ Dowling - Pediatric research, 2021 - nature.com
vaccine delivery systems that mimic the size, shape, and surface chemistry of pathogens. From
an immunoengineering stance, the ideal vaccine … aqueous lumen with sizes ranging from …

In vivo fate and intracellular trafficking of vaccine delivery systems

J Lee, D Kim, J Byun, Y Wu, J Park, YK Oh - Advanced Drug Delivery …, 2022 - Elsevier
… , researchers can hope to develop an optimal vaccine … The size of the vaccine delivery
system can modulate the in … In this study, nanoparticle with sizes higher than 150 nm was …