[HTML][HTML] New Therapies and Strategies to Curb HIV Infections with a Focus on Macrophages and Reservoirs
…, MS Sinicropi, J Ceramella, D Iacopetta, R Salpini… - Viruses, 2024 - mdpi.com
… HIV infection is represented by CD4+ T cells, the virus also has the ability to infect myeloid
cells such macrophages and monocytes … and inflammatory responses in SIV models, [283] …
cells such macrophages and monocytes … and inflammatory responses in SIV models, [283] …
T cell-tropic HIV efficiently infects alveolar macrophages through contact with infected CD4+ T cells
AE Schiff, AH Linder, SN Luhembo, S Banning… - Scientific reports, 2021 - nature.com
… rates may be different compared to tissue resident … and NHPs infected with T-tropic HIV or
SIV shows that infection of tissue … Monocytes and CD4+ T cells were then isolated by CD14+ …
SIV shows that infection of tissue … Monocytes and CD4+ T cells were then isolated by CD14+ …
Glycan dependent phenotype differences of HIV-1 generated from macrophage versus CD4+ T helper cell populations
EJ Heeregrave, J Thomas, TM van Capel… - Frontiers in …, 2023 - frontiersin.org
… virus (SIV) is more infectious than T cell-derived virus (30). Further… CD4 enriched lymphocytes
and monocyte derived … of cell capture and subsequent transfer to CD4 + T lymphocytes, …
and monocyte derived … of cell capture and subsequent transfer to CD4 + T lymphocytes, …
The youngbloods. Get together. Hypercoagulation, complement, and NET formation in HIV/SIV pathogenesis
… + T cells from individuals with chronic HIV infection express … with different pathogenic
outcomes of SIV infection decisively … alter the degree of activation of monocytes and T cells (75). …
outcomes of SIV infection decisively … alter the degree of activation of monocytes and T cells (75). …
T cell-inducing vaccine durably prevents mucosal SHIV infection even with lower neutralizing antibody titers
…, CF Quarnstrom, KA Walter, TJ Ketas, T Legere… - Nature medicine, 2020 - nature.com
… receptor-expressing monocytes and natural killer (NK) cells, were … an overlapping SIV-Gag
peptide pool to activate T cells in situ … protective immunity against diverse pathogens such as …
peptide pool to activate T cells in situ … protective immunity against diverse pathogens such as …
Combination immune checkpoint blockade to reverse HIV latency
…, JL Anderson, RP Sékaly, R Fromentin… - The Journal of …, 2020 - journals.aai.org
… In SIV-infected macaques on ART, there is also … CD4 + T cells with monocytes in the
presence of SEB, which are known to express high levels of IC ligands, followed by HIV infection …
presence of SEB, which are known to express high levels of IC ligands, followed by HIV infection …
Monocyte and CD4+ T-cell antiviral and innate responses associated with HIV-1 inflammation and cognitive impairment
…, V Valcour, P Sithinamsuwan, T Chalermchai… - Aids, 2020 - journals.lww.com
… of both CD4 + T cells and monocytes correlated with soluble … gene programs exhibit different
patterns of association with … upregulated in monocytes during HIV-1 infection described [58–…
patterns of association with … upregulated in monocytes during HIV-1 infection described [58–…
Siglec-9 defines and restrains a natural killer subpopulation highly cytotoxic to HIV-infected cells
… To further ensure the exclusion of monocytes from our … , we used HIV-infected primary CD4
+ T cells as target cells and … and differentiated phenotype during HIV/SIV infection, such as …
+ T cells as target cells and … and differentiated phenotype during HIV/SIV infection, such as …
Enhancement of CD4 Binding, Host Cell Entry, and Sensitivity to CD4bs Antibody Inhibition Conferred by a Natural but Rare Polymorphism in the HIV-1 Envelope
AN Ratcliff, CM Venner, AS Olabode, J Knapp… - Journal of …, 2022 - Am Soc Microbiol
… /CCR5 cells (no surface CD4), we observed no infection with … with various HIV-1 strains
leads to inhibition of infection (26… primary CD4 + T cells, but again, A74.N425.wt and A74.K425…
leads to inhibition of infection (26… primary CD4 + T cells, but again, A74.N425.wt and A74.K425…
Walk on the wild side: SIV infection in African non-human primate hosts—from the field to the laboratory
AJ Jasinska, C Apetrei, I Pandrea - Frontiers in Immunology, 2023 - frontiersin.org
… HIV/SIV infections (142) (1): loss of the CD4+ T cells, the … , probably regulated by monocytes
early in the acute infection. This … SIV infection has a different influence on DNA methylation …
early in the acute infection. This … SIV infection has a different influence on DNA methylation …