[HTML][HTML] Immune checkpoint modulation enhances HIV-1 antibody induction

…, X Chen, C Cheng, AH Ellebedy, R Parks… - Nature …, 2020 - nature.com
… during HIV-1 infection have higher levels of CD4+ Tcells such as B cells, CD4+ and CD8+
T cells as well as less common immune cell populations, such as monocytes, dendritic cells, …

Persistent Immune Activation in HIV-1–Infected Ex Vivo Model Tissues Subjected to Antiretroviral Therapy: Soluble and Extracellular Vesicle-Associated Cytokines

V Mercurio, W Fitzgerald, I Molodtsov… - JAIDS Journal of …, 2020 - journals.lww.com
… by upregulation of various cytokines, both soluble and EV-… LAI04 infection. Difference in
cytokine upregulation between viral strains may be related to the difference in the CD4 + T cell

[PDF][PDF] Isolation of Novel anti-SIV Monoclonal Antibodies from Rhesus Macaques

N Pedreño López - 2020 - scholarship.miami.edu
… a total of 24 SIV-specific mAbs isolated from two different cell … of infection, we reasoned
that the depletion of CD8+ T cellscells (monocytes, macrophages, neutrophils and dendritic …

[图书][B] Characterizing the immunogenicity of a therapeutic DNA vaccine and determinants of viral control in SIV-infected rhesus macaques with variable responses to …

H Tunggal - 2021 - search.proquest.com
… virusГspecific CD4 T cells in HIV and SIV infection is unclear. … =odies capa=le of neutralizing
many diverse strains of HIV) [104] or … autologous monocytes, culturing those monocytes with …

In silico model of infection of a CD4 (+) T-cell by a human immunodeficiency type 1 virus, and a mini-review on its molecular pathophysiology

A Vivanco-Lira, JR Nieto-Saucedo - arXiv preprint arXiv:2102.03876, 2021 - arxiv.org
… that the SIV from the Sooty mangabey originated the HIV-2 (… incorporation into several cell
lines, such as: monocyte-derived … an inhibitor of T cell activation by different mechanisms. The …

[HTML][HTML] Why the HIV reservoir never runs dry: clonal expansion and the characteristics of HIV-infected cells challenge strategies to cure and control HIV infection

CY Lau, MA Adan, F Maldarelli - Viruses, 2021 - mdpi.com
… a decline in CD4 T cells and the progression to AIDS, ART … other cell types, such as
macrophages, in diverse anatomic … studied as correlates of other soluble and lymphocyte markers …

Elucidating how HIV-1 infection influences CD4, CD8 and regulatory T cell phenotype and function

S Shahbaz - 2021 - era.library.ualberta.ca
… of Tregs in different subpopulations of HIV-infected individuals (… Although other CD4 expressing
cells such as monocytes, … the blocking of TIM-3 interaction with Gal-9 using soluble TIM-…

[HTML][HTML] Phagocytosis by an HIV antibody is associated with reduced viremia irrespective of enhanced complement lysis

…, H Henderson, R Agnor, L Gao, T Bruel… - Nature …, 2022 - nature.com
… day 56 and incubated with SIV mac239 gag pooled peptides. … for either T cells or
monocyte-derived dendritic cells (MDCs), we … The pro- and antiviral roles of complement in HIV

Development of a Novel In Vitro Primary Human Monocyte-Derived Macrophage Model To Study Reactivation of HIV-1 Transcription

ME Wong, CJ Johnson, AC Hearps… - Journal of …, 2021 - Am Soc Microbiol
CD4 + T cells, HIV-infected macrophages exhibit innate resistance to the cytopathic effects
of infection … Latently infected myeloid cells persist in SIV-infected macaques receiving ART …

[HTML][HTML] Immunological approaches to HIV cure

AR Ward, TM Mota, RB Jones - Seminars in immunology, 2021 - Elsevier
… immunodeficiency virus (HIV) infection has proven … yet HIV infection persists indefinitely in
a reservoir of cells, despite effective ART and despite host antiviral immune responses. An HIV