[HTML][HTML] The Impact of SIV-Induced Immunodeficiency on Clinical Manifestation, Immune Response, and Viral Dynamics in SARS-CoV-2 Coinfection
A Melton, LA Rowe, T Penney, C Krzykwa, K Goff… - bioRxiv, 2023 - ncbi.nlm.nih.gov
… Despite the marked decrease in CD4+ T cells in the SIV+ … subclustering analysis of
monocyte/macrophage and T cell clusters. … low CD4+ T cell counts due to advanced HIV/SIV …
monocyte/macrophage and T cell clusters. … low CD4+ T cell counts due to advanced HIV/SIV …
Elucidating how HIV-1 infection influences CD4, CD8 and regulatory T cell phenotype and function
S Shahbaz - 2021 - era.library.ualberta.ca
… of Tregs in different subpopulations of HIV-infected individuals (… Although other CD4 expressing
cells such as monocytes, … the blocking of TIM-3 interaction with Gal-9 using soluble TIM-…
cells such as monocytes, … the blocking of TIM-3 interaction with Gal-9 using soluble TIM-…
[HTML][HTML] Immunomodulation with IL-7 and IL-15 in HIV-1
JD Gunst, N Goonetilleke, TA Rasmussen… - Journal of Virus …, 2023 - Elsevier
… is highly expressed by monocytes and dendritic cells and is … T cells in a dose-dependent
manner, 26 while the different IL-15 … SIV vaccination prior to SIV challenge preserved the CD4 + …
manner, 26 while the different IL-15 … SIV vaccination prior to SIV challenge preserved the CD4 + …
[PDF][PDF] Impact of early antiretroviral therapy initiation and immunotherapy interventions on the dynamics of regulatory T cells during SIV-HIV infections
AY Diaz - 2022 - archipel.uqam.ca
… his crucial contribution to our SIV infection model. Thank you … HIV replication in CD4 T cells
since productive infection occurs … of various immune cells, including B and T cells, NK cells, …
since productive infection occurs … of various immune cells, including B and T cells, NK cells, …
Advances toward curing HIV-1 infection in tissue reservoirs
LJ Henderson, LB Reoma, JA Kovacs, A Nath - Journal of virology, 2020 - Am Soc Microbiol
… HIV infection of the resting memory CD4 T cells fulfills this … While monocyte-derived
macrophages can be persistently … Data from simian immunodeficiency virus (SIV) models suggest …
macrophages can be persistently … Data from simian immunodeficiency virus (SIV) models suggest …
Advances in SIV/SHIV non-human primate models of NeuroAIDS
S Moretti, S Virtuoso, L Sernicola, S Farcomeni… - Pathogens, 2021 - mdpi.com
… , only brain memory CD4+ T cells harbored SIV DNA in … macrophages in different tissues
from the same SIV-infected … time of infection blocked monocyte trafficking and SIV RNA is …
from the same SIV-infected … time of infection blocked monocyte trafficking and SIV RNA is …
The role and impact of Nef and Nef inhibitor in HIV-induced impairment of CD4 T-cells
D Mahesh - 2024 - d-scholarship.pitt.edu
… mononuclear cells (PBMCs), exploring various strains of HIV … To assess the cytotoxic effect
of HIV infection on CD4 T cells, … The culture supernatants were quantified for soluble immune …
of HIV infection on CD4 T cells, … The culture supernatants were quantified for soluble immune …
Role of macrophages in HIV pathogenesis and cure: NIH perspectives
J Joseph, W Daley, D Lawrence… - Journal of Leukocyte …, 2022 - academic.oup.com
… CD4+ T cells are considered the main targets of HIV infection… while HIV and SIV primarily
infect CD4+ T cells, monocytes … in different stages of untreated and treated HIV-1 infection. …
infect CD4+ T cells, monocytes … in different stages of untreated and treated HIV-1 infection. …
[HTML][HTML] Targeting HIV-1 reservoirs in T cell subsets
… is possible to target HIV reservoirs in CD4 + T cells at various … 4A) from human peripheral
blood monocytes (PBMC). After … that HIV-1 latent infection could be established in naïve T cells, …
blood monocytes (PBMC). After … that HIV-1 latent infection could be established in naïve T cells, …
Simian immunodeficiency virus-infected rhesus macaques with AIDS co-develop cardiovascular pathology and encephalitis
…, AD Miller, NN Abuelezan, R Burrack… - Frontiers in …, 2023 - frontiersin.org
… We and others have shown that blocking monocyte traffic or … we asked whether SIV infected
animals with AIDS codevelop … ten HIVE patients had CD4+ T cell counts < 200 cells. Single-…
animals with AIDS codevelop … ten HIVE patients had CD4+ T cell counts < 200 cells. Single-…