… used authentic SARS-CoV-2 to demonstrate that spike substitution D614G enhances viral
replication in the upper respiratory tract and increases neutralization susceptibility. These …

… A spike protein mutation D614G emerged and became dominant soon … D614G mutation
into an authentic wild-type SARS-CoV-2 strain, we demonstrate the importance of this mutation …

… authentic SARS-CoV-2 to demonstrate that the spike D614G … tract and increases the
susceptibility of the virus to neutralization by … on other emerging mutations in SARS-CoV-2, …

… coronavirus 2 (SARS-CoV-2) spike protein acquired a D614G mutation early in … D614G
might also mediate neutralization escape that could compromise vaccine efficacy, sera from spike…

… D614G mutation in the spike protein of SARS-CoV-2 alters … neutralizing and immunodominant
sites on the SARS-CoV-2 … -19, the sensitivity of the recombinant SARS-CoV-2 S protein to …

… changes are observed in SARS-CoV-2 variants due to the … of the SARS-CoV-2 genome
contained the aspartic acid in spike … some of the conformations, giving some extra fitness to the …

… D480A/G escapes neutralizing antibody 80R, and immune pressure … SARS-CoV-2, with
extended human-to-human transmission, SARS-CoV-2 could also acquire mutations with fitness …

… L452R mutation with D614G and with the D614G mutation … by 13 amino acid changes,
contain diverse mutations in the … escape, transmissibility, and susceptibility to some treatments, …

… Emerging variants of SARS-CoV-2 that harbor genome mutations that may impact … mutations
across the genome, including several in the receptor-binding domain (RBD) of the spike …

… -residue mutations will not likely change viral sensitivity to neutralization unless they grossly
alter S … , which confers an apparent fitness advantage to the virus. It is not certain whether …