… Nlrp3-deficient mice were resistant to alcohol-induced … lipin-1 exacerbates steatosis and
hepatobiliary damage and leads to … and lipid metabolism, is reduced in patients with ALD (130). …

… induced by concanavalin A in mice, and SAP130–Mincle signaling induces liver … of
alcoholic liver disease, and SAP130 exacerbates alcohol-induced liver injury by inducing …

… the setting of alcohol-induced liver injury. In terms of focused … of ligand spliceosome-associated
protein 130 (SAP130), the … coli RNA concluded in stimulating the NLRP3 inflammasome …

… of the Casp8-NLRP3 inflammasome loaded as cargo in small … -GluCer), spliceosome-associated
protein 130 (SAP130) and … a constitutively active GSDMD exacerbated liver injury (13) …

… of the Caspase 8-NLRP3 inflammasome loaded as cargo in … (β-GluCer), spliceosome-associated
protein 130 (SAP130), … constitutively active GSDMD exacerbated liver injury 13 , and …

… exacerbated liver inflammation and fibrosis in ALD via … against alcohol-induced liver injury
in an NLRP3 inflammasome-… to block liver steatosis and fibrosis in mice fed with HFD (130). In …

… on liver injury, we established a mouse model of CCL 4 -induced liver injury and liver fibrosis…
Subcutaneous CCl 4 administration has been successfully applied to induce liver injury and …

… In 2008, spliceosome-associated protein 130 (SAP130), an … Mincle exacerbates chronic
alcoholic liver injury caused by … and progression of chronic alcohol-induced liver injury (30). …

… Spliceosome-associated protein 130 exacerbates alcohol-induced liver injury by inducing
NLRP3 inflammasome-mediated IL-1β in mice. Am J Pathol 2018;188:967-980. 9) Gao B, …

… as LPS into the liver through the portal vein activates NLRP3 … ligand called
spliceosome-associated protein 130 (SAP130) … in attenuation of alcohol-induced hepatic …