… and mast cell responsiveness, sensitization, stimulation, and … by inhibiting the IgE-FcεRI-mediated
pathway to neutralizing serum … and anaphylaxis score in NOD scid gamma mice [118]. …

… understanding of these antibody-independent receptors in MCs have … of mast cell degranulation
thresholds or directly activate mast … BTK is crucial for FcεRI-mediated MC activation and …

… Mast cells (MCs) play a key role in the development of … Cells were sensitized with mouse
monoclonal antibodies of the … There is also a LAT-independent MC activation pathway …

… mast cells have “significantly enhanced FcεRImediated signaling, … In mice bred to be deficient
in mast cells (kit mutation), the … The increase in histamine levels can occur independently of …

… Independent epidemiological case–control studies … by fewer food allergy reactions, such as
symptoms, mast cell … the signaling cascades of both FcεRI-mediated protein kinases (Syk, Lyn…

… or inhibit FcεRI-mediated mast cell activation depending on … due to mast cell liberators that
activate them independently of … but is also a food allergen potentially inducing severe clinical …

… dose-independent manner following PC treatment (Figure 5B). … Additionally, we found
that mast cell degranulation was … Free PS and Lyso-PS can enhance FcϵRI-mediated MC …

… recruitment of neutrophils in mice because of their binding … have been partially explored in
human mast cells (15, 53) but … an FcεRI-mediated activation pathway in both cell types. IL-8 …

… Th2 responses to food, implying the existence of another T-cell-independent pathogenesis
for … , inhibiting mast cell and basophil activation, and blocking FcεRI-mediated inhibition of toll-…

… of the possible IgE-independent MC activation pathways [3]. … —in the indications of chronic
spontaneous urticaria and atopic … -alpha)/cachectin by mouse mast cells stimulated via the Fc …