… of paroxetine and pravastatin, further studies in diabetic patients are urgently needed to
clarify the clinical significance of the potential interaction between these two medications. …

… Since our review in 2015 [Citation10], few studies have evaluated the pharmacokinetic impact
of drug–drug interactions in human clinical trials for fluvastatin, lovastatin, and pitavastatin. …

… which may result in polypharmacy and the risk of drug interaction is increased with the …
explore the clinical significance of the specific interaction between statins and other drugs and to …

… A growing number of reports have been indicating the potential clinical significance of plain
myalgia. Although data based on observational studies and registries indicated an incidence …

… drug interactions in the setting of polypharmacy [46]. Alternatively, this trend might reflect a
reduced capacity for statins to impact … clinical significance of ezetimibe as an add-on to statin …

… effects, the NLA Statin Muscle Safety Task Force proposed more precise terminology to
account for the full range of statin-… direct myotoxic effects or drug-drug interactions with statins. …

… DDIs leads to adverse clinical consequences. These clinically significant DDIs are particularly
… Reduce the statin dosage to the lowest effective dose and consider using a fibrate other …

… initiating statin treatment, contraception methods should be discussed because statins may
have teratogenic effects… , with greater potential for drug interactions when prescribing a statin. …

… The findings of other OGLDs have similarly important clinical implications: first, the lack of
disproportion for the whole pharmacological class when used alone argues against the …

… effects of statin remains suboptimal. Although excellent reviews for the statin adherence has
been published to highlight the clinical … and cyclosporine drug-drug interactions in transplant …