Advances in the field of intranasal oxytocin research: lessons learned and future directions for clinical research

DS Quintana, A Lischke, S Grace, D Scheele… - Molecular …, 2021 - nature.com
… effects, methodological shortcomings, and a poor understanding of … However, general
methodological issues such as the … and statistically underpowered candidate gene studies [50], as …

How can intranasal oxytocin research be trusted? A systematic review of the interactive effects of intranasal oxytocin on psychosocial outcomes

A Mierop, M Mikolajczak, C Stahl… - Perspectives on …, 2020 - journals.sagepub.com
… More research that advances our understanding of the … analyzed in the current review reached
sufficient statistical … points to important concerns about the current state of IN-OT research. …

Improving the precision of intranasal oxytocin research

A Winterton, LT Westlye, NE Steen… - Nature Human …, 2021 - nature.com
consideration of methodology, theory and reproducibility. … Oxytocin studies have historically
been statistically under-… practices, scholars can improve our understanding of the oxytocin

[HTML][HTML] Towards better hypothesis tests in oxytocin research: Evaluating the validity of auxiliary assumptions

DS Quintana - Psychoneuroendocrinology, 2022 - Elsevier
… in terms of theory, experimental design, and statistical inference… our understanding of oxytocin’s
role in cognition and behavior. … : critical considerations for intranasal oxytocin research in …

Effects of intranasal oxytocin on pain perception among human subjects: A systematic literature review and meta-analysis

S Lopes, F de Lima Osório - Hormones and Behavior, 2023 - Elsevier
… presented statistical significance in terms of the interventions' … -analysis of studies assessing
the effects of intranasal OXT on … Both authors assessed the studies' methodological quality …

[HTML][HTML] Most oxytocin administration studies are statistically underpowered to reliably detect (or reject) a wide range of effect sizes

DS Quintana - Comprehensive Psychoneuroendocrinology, 2020 - Elsevier
statistical power of intranasal oxytocin administration studies … (For interpretation of the
references to colour in this figure … intensive clinical interventions, half of the non-significant studies (…

[HTML][HTML] “Less is more”: a dose-response account of intranasal oxytocin pharmacodynamics in the human brain

D Martins, K Brodmann, M Veronese… - Progress in …, 2022 - Elsevier
… Colors depict average T-statistics of all voxels within each … Two possible reasons might have
contributed to the lack of … larger studies should focus on expanding our understanding of the …

Intranasal oxytocin as a potential therapeutic strategy in post-traumatic stress disorder: a systematic review

G Giovanna, S Damiani, L Fusar-Poli… - …, 2020 - Elsevier
… The fourteen studies included in the present review provide … meaning of these measures
should be interpreted with caution". … in the present review, as summarized in Table 3, statistical

A systematic review of human paternal oxytocin: Insights into the methodology and what we know so far

S Grumi, A Saracino, BL Volling… - Developmental …, 2021 - Wiley Online Library
… model research and the number of methodological issues that … also report pre- and
post-administration descriptive statistics … , research efforts should be dedicated to understanding

Intranasal oxytocin for negative symptoms of schizophrenia: systematic review, meta-analysis, and dose-response meta-analysis of randomized controlled trials

M Sabe, N Zhao, A Crippa, GP Strauss… - International Journal of …, 2021 - academic.oup.com
… crossover studies, a detailed examination of methodology was … The I 2 statistic was used to
measure the inconsistency … concerns the pharmacokinetic profile of intranasal oxytocin. The …