… –139 kg or ≥ 140 kg were given up to 6.75 g or 9 g every … piperacillin steady-state
trough concentrations for the same patients on two different dosing regimens: Piperacillin–tazobactam …

… pharmacokinetic analysis of CI piperacillin/tazobactam, and to … steady-state concentration
(Css) of increasing piperacillin/… PIP is typically co-administered with tazobactam (TAZ), a beta-…

… intravenously at a dose of 500 mg/500 mg/250 mg 4 times-daily [35], and piperacillin/
tazobactam administered by continuous infusion at a dose of 4.5/0.5 grams 4 times-daily effectively …

… administration to achieve appropriate pharmacodynamic targets. This review synthesizes
important pharmacokinetic elements for piperacillin-tazobactam … s pharmacokinetic parameters …

… It is strongly recommended to administer piperacillin–tazobactam as a prolonged (ie
continuous or … Total piperacillin and tazobactam concentrations were predicted at steady-state. …

… interval at steady state (50% fT >MIC ); (2) unbound piperacillin concentrations above the …
physiology and pathophysiology was considered, given the sparse sampling in this study. The …

… was at steady state (at least 4 doses of TZP had been given). The serum creatinine level
was measured with morning clinical labs during the day of pharmacokinetic sampling and was …

… piperacillin-tazobactam administered via intermittent infusions in combination with tobramycin
was synergistic against a piperacillin… to achieve the steady-state trough concentration at 0 …

… administration of piperacillin-tazobactam has been proposed as a valuable alternative to
traditional intermittent administration … outcomes of piperacillin tazobactam dosing regimens, …

… Piperacillin-tazobactam was administered at a median (IQR) daily … for optimizing CI
piperacillin-tazobactam exposure were … Median (IQR) piperacillin and tazobactam free …