[HTML][HTML] Extended versus Intermittent Infusions of Piperacillin-Tazobactam in Patients with Febrile Neutropenia

DJ Reeves - 2020 - jhoponline.com
… The study’s primary outcome measure was defervescence within 24 hours of piperacillin-tazobactam
administration. Secondary outcome measures included time to defervescence, …

Altered Pharmacokinetics and Pharmacodynamics of Drugs in the Intensive Care Unit

F Hefny - 2023 - era.library.ualberta.ca
… capsules prior to administration was significantly associated with … from capsules prior to
administration were associated with … nimodipine formulation and administration techniques are …

Early target attainment with continuous infusion meropenem and piperacillin/tazobactam and utilization of therapeutic drug monitoring in critically ill patients: a …

S Dräger, M von Rotz, ND Labhardt… - Open Forum …, 2023 - academic.oup.com
… 24 hours for piperacillin/tazobactam, respectively. The preparation and administration of the
… (meropenem) and C steady state concentration (piperacillin). Accordingly, thresholds of 20 …

Challenges in predicting the pharmacokinetics of drugs in premature and mature newborns: example with piperacillin and tazobactam

JW Fisher, D Mehta, M Li, X Yang - Clinical Pharmacology During …, 2022 - Elsevier
… for the intravenously administered combination drugs piperacillin (PIP) and tazobactam (TAZ), …
coefficient values will result in lower and higher predicted plasma levels at steady state. …

[PDF][PDF] István Vincze"*, Rita Czermann*, Zsuzsanna Nagy", Mária Kovács", Michael Neely", Róbert Farkas", Ibolya Kocsis", Gellért Balázs Karvaly" and Csaba Kopitkó

Z Nagy - J. Clin. Med, 2022 - researchgate.net
… Optimally, however, PK/PD targets, eg, steadystate free piperacillin concentrations attaining
… No bolus dose of piperacillin/tazobactam will be administered at the beginning of treatment. …

Pharmacokinetic-Pharmacodynamic and Clinical Considerations for Extended-and Continuous-Infusion Antibiotics

AM Masich, NE Omecene, J Lai, R Ong… - Clinical Microbiology …, 2023 - Elsevier
… to be assessed prior to steady state and only necessitates one … dose administered over
24 hours. Vancomycin concentrations are obtained at 24-hour intervals until a steady state

Comparison of pharmacokinetics software for therapeutic drug monitoring of piperacillin in patients with severe infections

AS Rodríguez-Báez, M Jiménez-Meseguer… - European Journal of …, 2024 - ejhp.bmj.com
… Blood samples (4 mL) were collected at steady state before the next dose and at the …
augmented renal clearance receiving piperacillin-tazobactam administered by continuous infusion. …

[HTML][HTML] Tolerability, Safety, Pharmacokinetics and Drug Interaction of Cefotaxime Sodium–Tazobactam Sodium Injection (6: 1) Following Single and Multiple …

N Chen, LN Sun, WH Hu, YY Wang, LJ Xie… - … in pharmacology, 2020 - frontiersin.org
pharmacokinetics and excretion of cefotaxime and tazobactam were not affected by the
co-administration … concentrations of CTX and TAZ all appeared to be at a steady state on day 6. …

[HTML][HTML] A systematic review of the pharmacokinetics and pharmacodynamics of novel beta-lactams and beta-lactam with beta-lactamase inhibitor combinations for the …

E Rando, E Novy, F Sangiorgi, G De Pascale… - International Journal of …, 2024 - Elsevier
… and administration regimens for ceftolozane/tazobactam … 3 g of ceftolozane/tazobactam
regimens administered in a 1-… (FTA) for ceftolozane steady-state exposure using EUCAST …

… of Area Under the Concentration–Time Curve on the Prevalence of Vancomycin-Induced Nephrotoxicity in Combination With Tazobactam/Piperacillin or Cefepime: A …

N Okada, Y Izumi, A Nakamoto, M Chuma, M Goda… - Clinical Therapeutics, 2021 - Elsevier
… The steady-state vancomycin trough concentration in blood samples collected within 30 …
vancomycin administration after the second or later day of vancomycin administration was …