… with meropenem or piperacillin-tazobactam, daily TDM of … samples were taken in the
pharmacokinetic steady state (≥ … or 4.5 g piperacillin-tazobactam was administered over 30 min…

… with agents like piperacillin–tazobactam. Furthermore, to … administration in terms of how
or if the entire dose was given. … in the tubing and not administered to the patient. More than a …

… The area under the concentration-time curve from 64 to 88 h (AUC 64–88 ; ie, steady-state
AUC … The schedule of drug administration used in this study and the Monte Carlo simulations …

… In addition, we chose to sample patients at a steady state … compared to cefotaxime and
piperacillin/tazobactam. The reason … All our patients were on intermittent antibiotic administration …

… piperacillin concentration represented a steady-state concentration. Hence, pharmacokinetic/
pharmacodynamic … Second, the administration period was short since the study protocol …

… the first administration is greater than what we found in this study. For piperacillin-tazobactam, …
A few studies have analyzed both piperacillin and tazobactam pharmacokinetics in CRRT …

Background: Piperacillin (Pip)/tazobactam (Taz) is a broad-spectrum antimicrobial agent that
has been commonly used in the intensive care unit for severe and life-threatening infections…

… Neither cefepime nor piperacillin/tazobactam improved the … -carbapenemase-producing
given the high susceptibility of … conclusions may not be drawn given the lack of statistical …

… L/h, and volume of distribution at steady state (V ss ) was 9.16 L; each of these parameters
was independent of the administered dose. Other analyses demonstrated that dalbavancin is …

… surgery and after a 24 h steady-state period. The PK/pharmacodynamic (PD) target was to
… Piperacillin/tazobactam was the most administered β-lactam antibiotic (75%). The serum/…