… Despite its devastating effects, very little is known about how ZIKV infection produces …
infection in the mouse brain and spinal cord resulting in massive neurodegeneration of infected …

… to neuronal development. Both isolates downregulated cognitive and behavioral development
… Acute and chronic neurological consequences of early-life Zika virus infection in mice. Sci …

… of the BBB permeability by ZIKV could be strain dependent (16). … Zika virus infection has
demonstrated to activate type II IFN, and supress type I and type II IFN signaling. This differential …

… We then examined if infection outcomes were due to differential expression of IFN-λ or its …
experimental evidence that there is strain-dependent phenotypic heterogeneity in pregnancy …

… b–g Analyses of in utero brain development of E18.5 mouse … other common viral infections
70 . In the absence of severe … lineages was driven by differential selective pressures is still an …

… compromises the identity and/or function of differentiating/differentiated glial cells, we infected
astrocytes-hNS1 at a MOI of 1, and compared the expression of the glial transcripts GFAP, …

… difference in virulence between two commonly used ZIKV strains. Our data further define
the effect … The association between Zika virus infection and microcephaly in Brazil 2015–2017: …

… here, we infected mature neuronal cells derived by differentiation of human SH… strain-dependent
differences in viral protein levels in neurons that were less pronounced in non-neuronal …

… Moreover, the impacts on neural development by ZIKV infection are strain-dependent. … has
reported that ZIKV inhibits neuronal differentiation in a cell-strain-dependent manner, which is …

… in the outcomes due to the intrinsic dynamics of brain development. Apparently, … impact
of ZIKV infection in the WM may be critical during early childhood, given its pivotal role in brain …