… development of cognitive impairment, the area of stress has … stress, a precipitating factor in
Tau aggregation pathology. J … Propagation of tau pathology in a model of early Alzheimer’s …

… responses to stress affecting various cognitive functions such … lifetime stress and stressful
conditions on the precipitation of … initially affected in AD showing Tau pathology [82]. Moreover…

… pathological cascade are shown. Chronic stress precedes and acts as a trigger for subjective
cognitive … from wild type mice mitigated amyloid and tau pathology, memory deficits, and …

… clarify whether stress mechanisms act to exacerbate tau pathology or tau influences stress-related
… mediating the effects of stress on neurodegeneration 22 and cognition 19 even in the …

… effects of stress and glucocorticoids towards the development of AD pathology. Recent
findings … against chronic stress-induced cognitive dysfunction and oxidative stress and slowed …

… Alzheimer's diseaseassociated tau pathology. Hum Mol Genet. 2021; 30(18): 1693-710. …
Stress acts cumulatively to precipitate Alzheimer's disease-like tau pathology and cognitive …

… -associated Tau-protein. However, the poor correlation between cognitive decline and amyloid
… gene encoding transmembrane glycoprotein, which acts as a receptor on the surface of …

… and cognitive outcomes known as ESCAPE project (effect of stress on cognitive aging,
physiology … , physiological, and cognitive variables was studied to establish that stress can lead to …

… a precipitating role for chronic environmental stress and … In light of the limited cognitive
benefit of the direct antagonism … , age, Aβ), act cumulatively to precipitate AD pathology [26]. …

… secretion of GCs acting on a variety of organs to cope with stress during the process of …
pathophysiology of AD. Their roles in cognitive function, synaptic plasticity, and Aβ/Tau pathology …