Nucleosome breathing facilitates cooperative binding of pluripotency factors Sox2 and Oct4 to DNA
… origin stems from an allosteric mechanism without any conformational change in DNA and is
… heterogeneity of fully wrapped and partially unwrapped structures with varying unwrapped …
… heterogeneity of fully wrapped and partially unwrapped structures with varying unwrapped …
Structural Plasticity of Pioneer Factor Sox2 and DNA Bendability Modulate Nucleosome Engagement and Sox2-Oct4 Synergism
EN Nikolova, FC Malaga Gadea - Available at SSRN 4207965 - papers.ssrn.com
… While Sox2 adopts a DNA-bound like conformation at a strong nucleosome complex near
… To further gain insight into the synergistic binding of Sox2 and Oct4 on nucleosomes, we …
… To further gain insight into the synergistic binding of Sox2 and Oct4 on nucleosomes, we …
In silico identification of natural product inhibitors against Octamer-binding transcription factor 4 (Oct4) to impede the mechanism of glioma stem cells
C Nayak, SK Singh - Plos one, 2021 - journals.plos.org
… as initial structures for computing 50ns MD simulation. The … maintained the structural
conformation with an approximate … analysis were executed to obtain insight into the protein …
conformation with an approximate … analysis were executed to obtain insight into the protein …
Dynamics of Oct4 and Sox2 on the Nucleosome
MM Valdimarsson - skemman.is
… DNA binding by Sox2, both partners change conformation to … 90’s and the following wave
of computational analysis of proteins … (A) Structure of Sox2/Oct4 bound to the NCP at the DNA …
of computational analysis of proteins … (A) Structure of Sox2/Oct4 bound to the NCP at the DNA …