… structural basis for recognition of immune receptors by superantigens, we show that their
binding … cases in the USA are attributed to Staphylococcal enterotoxins (13). In addition, T-cell …

… findings from this work proves that superantigen properties … Conversely, MHC class II-bound
superantigens achieve TCR … the CDR binding pockets that are more conserved among TCR …

… staphylococcal enterotoxin C (SEC) in complex with the mouse Vβ8.2 chain revealed that
SEC binds to the Vβ chain in a cleft between … , this revealed a structural basis as to how SAgs …

… Zn 2+ by EDTA completely abolished MHC class II binding. … a range of different binding
affinities (from nanomolar to … binding of the peptide and of staphylococcal enterotoxin B to …

… molecules also bind via a distinct structurally conserved domain … The superantigen binding
sites are located well away from … be blocked by peptide mimetics of the superantigen domain. …

… aureus that bind directly to major histocompatibility complex (… staphylococcal enterotoxin
A (SEA) and staphylococcal … the IFN-γ depletion and isotype antibody groups was abolished, …

… may also be facilitated or exacerbated by those non-specific stimuli … when a specific IgE
antibody binding to a broad panel of … a) T cell superantigen: SAgs have superantigen activity and …

… , superantigens do not bind to CDR3, but instead bind T cells … of PBMCs by staphylococcal
Enterotoxin C1, CD25 + FoxP3 … primary infection results in abrogated memory T cell responses…

… 36% amino acid identity to staphylococcal enterotoxin A (SEA) (… -specific antibodies could
abrogate the mitogenic effects of … removes the ribosomal binding site (RBS) from the plasmid, …

… from human aortic endothelial cells (HAECs) and human umbilical vein endothelial cells (HUVECs)
and abolished … We recently demonstrated that staphylococcal enterotoxin C (SEC) …