Morphological determinants of carbon nanomaterial-induced amyloid peptide self-assembly

Y Xing, Y Sun, B Wang, F Ding - Frontiers in Chemistry, 2020 - frontiersin.org
… of amyloid filaments following graphite's hexagonal lattice … ) in Alzheimer's disease and the
11-residue non-amyloid-β core of … -molecular distances and orientations. All simulations were …

Amyloid beta peptides electrochemistry: A review

AM Chiorcea-Paquim, AM Oliveira-Brett - Current Opinion in …, 2022 - Elsevier
Alzheimer disease is a progressive age-related … with the dysfunctions of amyloid β (Aβ)
peptides and Tau protein-… observed by AFM onto highly oriented pyrolytic graphite (HOPG), were …

Electrical characteristics of amyloid beta peptides in vertical junctions

S Seo, J Lee, J Choi, GH Park, Y Hong, H Lee - NPG Asia Materials, 2021 - nature.com
… similar to those observed in Alzheimer’s patients. These … oli-Aβ on highly oriented
pyrolytic graphite (HOPG) electrodes (… S2c), inducing repulsive interactions with hydrophilic …

Amyloid aggregation at solid-liquid interfaces: Perspectives of studies using model surfaces

A Keller, G Grundmeier - Applied Surface Science, 2020 - Elsevier
… of numerous degenerative diseases such as Alzheimer’s disease, … Therefore, the interaction
of various amyloidogenic peptides … Similar to mica, highly oriented pyrolytic graphite (HOPG) …

Complete aggregation pathway of amyloid β (1-40) and (1-42) resolved on an atomically clean interface

PN Nirmalraj, J List, S Battacharya, G Howe, L Xu… - Science …, 2020 - science.org
… are the histopathological hallmarks of Alzheimer’s dementia (… used surfaces for protein
imaging such as graphite that can … orientation of the dodecamers on the graphene surface, we …

Interactions of the Aβ (1–42) Peptide with Boron Nitride Nanoparticles of Varying Curvature in an Aqueous Medium: Different Pathways to Inhibit β-Sheet Formation

N Sorout, A Chandra - The Journal of Physical Chemistry B, 2021 - ACS Publications
amyloid β (Aβ) peptide triggered by its conformational changes leads to the commonly known
neurodegenerative disease of Alzheimerorientation of the amino acid residues due to their …

Acetylenic Bond Layout Drives the Directional Assembly of Amyloid-like Peptides on Graphyne: Implications for Biomedical Safety Applications of Graphyne

X Wang, Y Hu, L Li, R Ju, X Han, H Tan… - ACS Applied Nano …, 2023 - ACS Publications
… in the natural abnormal assembly of amyloid β (Aβ) proteins. … the graphene surface and
interact with adjacent peptides, … the graphyne surface in an armchair or zigzag orientation (Figure …

Design of Peptides that Fold and Self-Assemble on Graphite

J Legleiter, R Thakkar, A Velásquez-Silva… - Journal of Chemical …, 2022 - ACS Publications
… 370 K), with different initial orientations relative to the graphite surface, and using different
surface, and steric interaction with the graphite would preclude planar backbone structure. …

Molecular Tuning of the Nano–Bio Interface: Alpha-Synuclein's Surface Targeting with Doped Carbon Nanostructures

E Alimohammadi, A Nikzad, M Khedri… - ACS Applied Bio …, 2021 - ACS Publications
… (12) In this study, only the NAC domain (non-amyloid β … fibrils, and after interacting with αβ
peptides, the fibril formation was … method, the interactions of α-synuclein and the best structure

Nanomaterials for modulating the aggregation of β-amyloid peptides

Y Huang, Y Chang, L Liu, J Wang - Molecules, 2021 - mdpi.com
amyloid-β (Aβ) peptides in the brain has been recognized as the major hallmark of Alzheimer’…
were greatly enhanced due to its special surface orientation and conformation (Figure 2A) […