The choroid plexus (CP) is a structure in the brain ventricles that produces the main part of
the cerebrospinal fluid (CSF). It is covered with specialized cells which show epithelial …

… astrocytic endfeet facing the blood–brain barrier as two major isoforms (M1 and M23), which
are organized in structures known as orthogonal arrays of particles (OAPs) [4]. Clinical and …

… The monomers combine into tetramers, but each of them functions as a separate channel
[93]. AQP4 can be arranged in supramolecular structures called orthogonal arrays of particles (…

… The four monomers form a central pore whose function has … in supramolecular structures
called orthogonal arrays of particles (… the formation of orthogonal structures or matrices of the …

… the structure of AQP4: in 2004, Furman discovered two isoforms of AQP4, M1 and M23, the
latter forming into large arrays to create protein rafts called orthogonal arrays of particles or …

… In the plasma membrane AQP4 monomers assemble to form tetramers, and tetramers
further assemble to form orthogonal arrays of particles (OAPs) (22). The size of OAPs is directly …

… brain structure and molecular water transport. Yet, no studies have systematically examined
how these abnormalities in structure and water transport correlate with glymphatic function. …

… a high-order complex, known as orthogonal array particles (OAP), are related to the water
gating mechanism.[13] Also, the size of the resulting OAP structure is related to the ratio of the …

… It is known that the M23-AQP4 isoform is critical to forming membrane OAPs (orthogonal
arrays of particles), and an M23-AQP4-null mouse has been generated demonstrating massive …

… The advantages of CBAs are chiefly attributed to the preservation of intact spatial conformation
and/or orthogonal arrays of particle structure (OAPs) of native AQP4, which has a higher …