[HTML][HTML] Nucleolin: a cell portal for viruses, bacteria, and toxins
… characteristics that make nucleolin able to … nucleolin ability to interact with nucleic acids,
with proteins, but also with carbohydrates and lipids. This modular multivalence allows nucleolin …
with proteins, but also with carbohydrates and lipids. This modular multivalence allows nucleolin …
[HTML][HTML] Anti-nucleolin aptamer AS1411: an advancing therapeutic
A Van den Avont, N Sharma-Walia - Frontiers in Molecular …, 2023 - frontiersin.org
… Respiratory Syncytial Virus (RSV) has been shown to use nucleolin as a functional
receptor that passively interacts with fusion proteins (F proteins) (Figure 3). F proteins are …
receptor that passively interacts with fusion proteins (F proteins) (Figure 3). F proteins are …
[HTML][HTML] Cancer stem cells and nucleolin as drivers of carcinogenesis
LS Carvalho, N Gonçalves, NA Fonseca, JN Moreira - Pharmaceuticals, 2021 - mdpi.com
… structure of nucleolin consists of three different functional … The N-terminal of nucleolin
varies in length among species. … of multiple protein partners for nucleolin. The central domain …
varies in length among species. … of multiple protein partners for nucleolin. The central domain …
[HTML][HTML] Nucleolin acts as the receptor for C1QTNF4 and supports C1QTNF4-mediated innate immunity modulation
SK Vester, RL Beavil, S Lynham, AJ Beavil… - Journal of Biological …, 2021 - ASBMB
… nucleolin is mediated by the second C1q-like domain of C1QTNF4 and the C terminus of
nucleolin… Our results suggest that nucleolin may serve as a docking molecule for C1QTNF4 and …
nucleolin… Our results suggest that nucleolin may serve as a docking molecule for C1QTNF4 and …
Nucleolin discriminates drastically between long-loop and short-loop quadruplexes
… We investigate herein the interaction between nucleolin (NCL) and a set of G4 sequences
derived from the CEB25 human minisatellite that adopt a parallel topology while differing in …
derived from the CEB25 human minisatellite that adopt a parallel topology while differing in …
Exploring structural determinants and the role of nucleolin in formation of the long-range interactions between untranslated regions of p53 mRNA
A Kiliszek, W Rypniewski, L Błaszczyk - RNA, 2023 - rnajournal.cshlp.org
… This study explores structural determinants of long-range … We demonstrate that the 8-nt
bulge motif plays a key structural … of the p53 translation regulators, nucleolin, displays an RNA …
bulge motif plays a key structural … of the p53 translation regulators, nucleolin, displays an RNA …
Nucleolin‑based targeting strategies in cancer treatment: Focus on cancer immunotherapy
S Thongchot, K Aksonnam… - International …, 2023 - spandidos-publications.com
The benefits of treating several types of cancers using immunotherapy have recently been
established. The overexpression of nucleolin (NCL) in a number of types of cancer provides …
established. The overexpression of nucleolin (NCL) in a number of types of cancer provides …
Molecular insights into the interaction of CAG trinucleotide RNA repeats with nucleolin and its implication in polyglutamine diseases
… expanded CAG RNA and the nucleolin (NCL) protein triggers the … structure of the r(CAG) 5
oligo that comprises a full A′-form helical turn with widened grooves. Based on this structure, …
oligo that comprises a full A′-form helical turn with widened grooves. Based on this structure, …
A novel role for nucleolin in splice site selection
… Finally, upon nucleolin knockdown we show activation of latent splicing in hundreds of coding
transcripts having important cellular functions. We thus propose nucleolin, a component of …
transcripts having important cellular functions. We thus propose nucleolin, a component of …
[HTML][HTML] Insights into the binding mode of AS1411 aptamer to nucleolin
… physical properties like nucleolin and GQ. By searching the RCSB PDB database using
nucleolin as the keyword (as of 19.7.2022), we can only retrieve 13 structures determined by …
nucleolin as the keyword (as of 19.7.2022), we can only retrieve 13 structures determined by …