… of action of DNA polymerases. The structural features of different DNA polymerase families
are … conformational dynamics of DNA polymerases from all known polymerase families during …

… DNA polymerase once predicted to be an inactive form, is a bona fide … found that Dpo2 is
a robust DNA pol in nucleotide incorporation but is devoid of the 3′–5′ exonuclease activity…

… This ring-like architecture is unique among multisubunit DNA polymerases and resembles
an uninterrupted daisy chain of protein–protein interactions, wherein Pol32 is the only subunit …

… ) DNA polymerase, which possesses the highest fidelity among known natural thermostable
DNA polymerases 23 and is … mass of Pfu DNA polymerase, at 90 kDa, is about twice that of …

… affect DNA polymerase activity. Both 9NN and 9N-NRQS displayed significantly reduced activity
for extending the canonical 3′-hydroxyl DNA … cause of the reduced DNA extension rate. …

… (10) We have previously shown that small-molecule inhibitors of the DNA polymerase
activity of Polθ not only elicit the synthetic lethality with BRCA genes previously predicted by …

… impedes growth by interfering with DNA replication. We hypothesized that the excess β clamp
sequesters the replicative DNA polymerase III (Pol III) to inhibit replication. As a test of this …

… on the proofreading reaction for T7 DNA polymerase remains to be studied. … activity for T7
DNA polymerase, we performed single turnover rapid quench experiments with synthetic DNA …

… Therefore, we have hypothesized that, by reducing the reaction rate of DNA polymerase at
the initiation and/or elongation steps, we can effectively enhance the priming accuracy and …

… Removal of bacterial DNA polymerases by our purification regime was … DNA synthesis
observed using the Pol- protein, which lacks the DNA polymerisation domain responsible for DNA …