Deep sequencing of HIV-1 reveals extensive subtype variation and drug resistance after failure of first-line antiretroviral regimens in Nigeria

K El Bouzidi, RP Datir, V Kwaghe, S Roy… - Journal of …, 2022 - academic.oup.com
… in similar analyses in sub-Saharan Africa, which found no … care at the time of the present
study. However, it was available to … from viral load testing were stored in the IHVN biobank. …

[PDF][PDF] The plight of rare diseases in southern Africa: health and social services policy recommendations

A David, MZ Alimohamed, G Modern, S Mbarak… - Qeios [Internet …, 2023 - academia.edu
… The situation is worse in sub-Saharan Africa (SSA), where … establishing a rare disease
biobank with the main focus on … We propose the establishment of a centralized registry of rare …

The East Africa Consortium for human papillomavirus and cervical cancer in women living with HIV/AIDS

Y Tong, E Orang'o, M Nakalembe, P Tonui… - Annals of …, 2022 - Taylor & Francis
… to HIV infection in people living in sub-Saharan Africa, as well as … sources, and to create a
centralized database for the U54 group, 4) … The Biobank is now housed in secure space and is …

Global Health security, multi-stakeholder collaboration, and pathogen sharing: Building a New Microbial Commons

C dos Santos Ribeiro - 2022 - research.vu.nl
… several outbreaks in sub-Saharan Africa, and in spite of many years of research into Ebola.
… Based on existing biobank models, how can ABS for pathogens and pathogen GSD be best …

[HTML][HTML] Current Status of Newborn Bloodspot Screening Worldwide 2024: A Comprehensive Review of Recent Activities (2020–2023)

BL Therrell, CD Padilla, GJC Borrajo… - International Journal of …, 2024 - mdpi.com
… 2021 report outlining a research project in which specimens from sub-Saharan Africa and
Asia … Neonatal Biobank in Detroit for storage under climate-controlled conditions and possible …

[HTML][HTML] Metagenomic pathogen sequencing in resource-scarce settings: lessons learned and the road ahead

C Yek, AR Pacheco, M Vanaerschot, JA Bohl… - Frontiers in …, 2022 - frontiersin.org
… of hemorrhagic fever viruses in sub-Saharan Africa, with … Transporting samples across long
distances to centralized … , and maintained in a central biorepository. Endemic public health …

Transferability of a European-derived Alzheimer Disease Genetic Risk Score across Multi-Ancestry Populations.

A Nicolas, B Grenier-Boley, R Sherva, Y Kim, M Kikuchi… - medRxiv, 2023 - medrxiv.org
… of the Alzheimer disease (AD) genetics. We extended its analysis in 16 … No association of
the GRS to AD was seen in sub-Saharan … In conclusion, a simple GRS captures shared genetic

[HTML][HTML] Decoding Genetics, Ancestry, and Geospatial Context for Precision Health

S Koyama, Y Wang, K Paruchuri, MM Uddin, SMJ Cho… - medRxiv, 2023 - ncbi.nlm.nih.gov
… as a prevalent hemolytic disease in Sub-Saharan Africa. Studying … factors in the Mass
General Brigham Biobank (MGBB). By … Second, MGBB participants are centralized in the greater …

Open-access geodata as a resource against infectious diseases

N Criscuolo - 2024 - research-collection.ethz.ch
… (C) Westward diffusion of cerebrospinal meningitis in sub-Saharan Africa prior to 1939 (56). …
In the absence of systematic surveillance, recent research efforts centralized open-access …

[HTML][HTML] A systematic evaluation of the performance and properties of the UK Biobank Polygenic Risk Score (PRS) Release

…, M Futema, Genomics England Research Consortium… - PLoS …, 2024 - journals.plos.org
… used this pipeline to benchmark the UK Biobank PRS Release. We have … Biobank Research
Access Platform, along with the associated phenotype definitions, to allow other researchers