[PDF][PDF] The genetic aetiology of oesophageal cancer in the South African black population

WC Chen - 2022 - wiredspace.wits.ac.za
genetic factors to OSCC risk in African populations. Recent genome-wide association studies
(GWAS) in Asian and European populations identified multiple genetic risk loci for OSCC, …

DNA methylation associated with mitochondrial dysfunction in a South African autism spectrum disorder cohort

S Stathopoulos, R Gaujoux, Z Lindeque… - … Research, 2020 - Wiley Online Library
… Finally, our study highlights the value of investigating the genetics of an understudied,
African ASD cohort for gaining insight into the etiology and endophenotypes of ASD. …

Clinical and regulatory challenges and opportunities for monoclonal antibodies in low-and middle-income countries: Lessons from COVID-19 and beyond

L Gieber, V Muturi-Kioi, S Malhotra, A Sitlani - Pharmaceutical Medicine, 2023 - Springer
… was a phase IIb trial enrolling almost 2000 sub-Saharan … is the limited availability of
biorepository facilities, which means … the EU, with centralized and mutual recognition procedures …

[引用][C] Seth C Inzaule, Sofonias K Tessema, Yenew Kebede, Ahmed E Ogwell Ouma, John N Nkengasong

Y Kebede, AU Prevention, AA Headquarters - 2021

Science without conscience is but the ruin of the soul: the ethics of big data and artificial intelligence in perioperative medicine

C Canales, C Lee, M Cannesson - Anesthesia & Analgesia, 2020 - journals.lww.com
… standard centralized approach, the study demonstrates the … that the genomic advances from
the BioBank will lead to genetic … benefit for women in sub-Saharan Africa because younger …

Protection of Personal Information Act 2013 and data protection for health research in South Africa

C Staunton, R Adams, D Anderson… - … Data Privacy Law, 2020 - academic.oup.com
Genomic research and biorepositories are dependent on accessing and sharing large
quantities of biological samples and associated data. The growth of international collaborative …

Enhancing equitable access to rare disease diagnosis and treatment around the world: a review of evidence, policies, and challenges

T Adachi, AW El-Hattab, R Jain… - … environmental research …, 2023 - mdpi.com
… and marketing authorization are centralized in the European … indicates that families in
sub-Saharan Africa are undoubtedly … of establishing the first RD biobank in the African continent, …

A plan for emergency shutdown and reopening for a consortium of biobanks

M Schmelz, M Sanderson-November… - Biopreservation and …, 2021 - liebertpub.com
study, we provide the questions and a summary of responses from the six biorepositories
If shipping is permitted by local regulations, make arrangements for centralized receiving and …

Gene expression in African Americans, Puerto Ricans and Mexican Americans reveals ancestry-specific patterns of genetic architecture

L Kachuri, ACY Mak, D Hu, C Eng, S Huntsman… - … genetics, 2023 - nature.com
… quantitative traits using summary statistics from the UK Biobank (UKB). Ancestry-matched …
Sub-Saharan African populations have the highest heterozygosity since the ancestors of all …

[HTML][HTML] Genetic consequences of the transatlantic slave trade in the Americas

SJ Micheletti, K Bryc, SGA Esselmann… - … of Human Genetics, 2020 - cell.com
… with genetic data. Here, we analyzed genotype array data from 50,281 research participants,
… shipping documents—illustrate that the current genetic landscape of the Americas is largely …