Neuropeptide regulation of secretion and inflammation in human airway gland serous cells
…, CCL Tong, P Papagiannopoulos… - European …, 2020 - Eur Respiratory Soc
… that defects in CFTR-dependent serous secretion contribute to … also secrete HCO 3 − during
VIP stimulation, if this occurs … cell surrogate, secrete HCO 3 − mainly through CFTR while Cl …
VIP stimulation, if this occurs … cell surrogate, secrete HCO 3 − mainly through CFTR while Cl …
Cellular and molecular architecture of submucosal glands in wild-type and cystic fibrosis pigs
W Yu, TO Moninger, AL Thurman… - Proceedings of the …, 2022 - National Acad Sciences
… genes were not well aligned to reference genes, primarily because of the lack of 3′ …
substance P causes rapid cell shrinkage, an assay of anion secretions, and at the end of stimulation…
substance P causes rapid cell shrinkage, an assay of anion secretions, and at the end of stimulation…
[HTML][HTML] The potential role and regulatory mechanisms of MUC5AC in chronic obstructive pulmonary disease
J Li, Z Ye - Molecules, 2020 - mdpi.com
… MUC5AC is mainly secreted by the goblet airway epithelium, … NCI-H292 cells and sulfur
dioxide-stimulated rat bronchitis … by activating wild-type CFTR-dependent, short circuit current …
dioxide-stimulated rat bronchitis … by activating wild-type CFTR-dependent, short circuit current …
PAR-2-activated secretion by airway gland serous cells: role for CFTR and inhibition by Pseudomonas aeruginosa
DB McMahon, RM Carey… - … of Physiology-Lung …, 2021 - journals.physiology.org
… in response to PAR-2 stimulation using Ca 2+ imaging and … of synergistic CFTR-dependent
PAR-2/VIPR secretion may … In contrast to mice, fluid secretion is largely intact when the …
PAR-2/VIPR secretion may … In contrast to mice, fluid secretion is largely intact when the …
CHANGES IN VASOACTIVE INTESTINAL PEPTIDE (VIP) AMOUNT IN CYSTIC FIBROSIS
P Semaniakou - 2020 - dalspace.library.dal.ca
… and submucosal glands of the conducting airways, stimulating … , fluid secretion from serous
cells is CFTR-dependent while … in response to ACh, VIP, substance P (SP) and nitric oxide …
cells is CFTR-dependent while … in response to ACh, VIP, substance P (SP) and nitric oxide …
The role of vasoactive intestinal peptide in pulmonary diseases
HL Zhong, PZ Li, D Li, CX Guan, Y Zhou - Life Sciences, 2023 - Elsevier
… Effects on TNF-α, IL-10, IL-12, and NO are mainly mediated through … CFTR-dependent
secretion is influenced by VIP. One study has previously disclosed that VIP triggers the stimulation …
secretion is influenced by VIP. One study has previously disclosed that VIP triggers the stimulation …
[HTML][HTML] Combined agonists act synergistically to increase mucociliary clearance in a cystic fibrosis airway model
NS Joo, HJ Cho, M Shinbashi, JY Choi, CE Milla… - Scientific reports, 2021 - nature.com
… to stimulate MCCV also stimulate submucosal gland secretion … forskolin mainly increased I
sc by stimulating anion secretion … are CFTR-dependent and -independent paths in synergistic …
sc by stimulating anion secretion … are CFTR-dependent and -independent paths in synergistic …
[PDF][PDF] Pulmonary neuroendocrine cells sense succinate to stimulate myoepithelial cell contraction
W Yu, TO Moninger, MV Rector, DA Stoltz, MJ Welsh - Developmental cell, 2022 - cell.com
… located within pig and human submucosal glands, a tissue that … gland contraction may
complement substance P stimulated … a limitation is that we primarily studied very young animals, …
complement substance P stimulated … a limitation is that we primarily studied very young animals, …
Chronic obstructive pulmonary disease and the modulation of CFTR by acute exposure to cigarette smoke
JW Hanrahan, A Abu-Arish, FH Wong… - … of Physiology-Cell …, 2022 - journals.physiology.org
… The delivery of fluid onto the airway surface, much of it … AMPK is activated by hydrogen
peroxide primarily through … stimulation of submucosal glands induced by noxious stimuli (184). …
peroxide primarily through … stimulation of submucosal glands induced by noxious stimuli (184). …
[HTML][HTML] Role of cystic fibrosis bronchial epithelium in neutrophil chemotaxis
… source of continuous release of proteases, mainly elastases, … release of DNA: CF neutrophils
are continuously stimulated … downstream than the CFTR-dependent ion transport alterations…
are continuously stimulated … downstream than the CFTR-dependent ion transport alterations…