Pharmacology of tyrosine kinase inhibitors in chronic myeloid leukemia; a clinician's perspective

D Pushpam, S Bakhshi - DARU Journal of Pharmaceutical Sciences, 2020 - Springer
… genes can affect drug delivery and efficacy of imatinib. … noted that normal pregnancies have
also occurred when patients were on … In patients with a history of pancreatitis dasatinib is the …

Approaches to Managing Philadelphia Chromosome Positive Chronic Myeloid Leukaemia Patients: A Short Review.

S Jayakumar, D Merin, A Krishna… - Systematic Reviews in …, 2022 - search.ebscohost.com
… remains the most successful anti leukemic therapy for CML. … Dasatinib: Dasatinib is at
the prominence of the second … Chronic myeloid leukemia may display varying tendency for …

Expectations and outcomes of varying treatment strategies for CML presenting during pregnancy

HF Robertson, D Milojkovic, N Butt… - British Journal of …, 2024 - Wiley Online Library
… the patient treated during pregnancy), five dasatinib and one … also confirm successful
pregnancy outcomes in patients … of chronic myeloid leukemia during pregnancy among patients

Treatment of CML in pregnancy

HF Robertson, JF Apperley - Hematology, 2022 - ashpublications.org
… , the outlook for patients with chronic myeloid leukemia (CML) … patient rapidly lost the response
after stopping dasatinib prior … Pregnancy and CML can now be successfully managed in …

Breastfeeding in a patient with chronic myeloid leukemia during tyrosine kinase inhibitor therapy

R Terao, M Nii, H Asai, F Nohara… - Journal of Oncology …, 2021 - journals.sagepub.com
… occurrence of chronic myeloid leukemia (CML) in pregnancy is 1 … Hematologic remission
was obtained, but the patient was … patient had a successful vaginal delivery after inducing labor

Effect of tyrosine kinase inhibitors on male fertility in patients with chronic phase chronic myeloid leukemia

G Nesr, S Claudiani, D Milojkovic, A Innes… - Leukemia & …, 2024 - Taylor & Francis
… of pregnancies in mated females [Citation10], dasatinib was … for 374 men) ended in a live
birth. The rate of congenital … case series reported successful pregnancies for fathers treated …

Fertility considerations in targeted biologic therapy with tyrosine kinase inhibitors: a review

A Rambhatla, MR Strug, JG De Paredes… - Journal of Assisted …, 2021 - Springer
… as specific therapy for chronic myelogenous leukemia (CML) in … the patient had a 3-month
washout and underwent a successful … who conceived while on dasatinib, pregnancy outcomes …

A case of ovarian stimulation for fertility preservation in a patient with Philadelphia chromosome‐positive acute lymphoblastic leukemia after treatment with dasatinib

T Ogawa, M Ogi, S Hirata - Journal of Obstetrics and …, 2021 - Wiley Online Library
… treatment of Ph+ALL and chronic myeloid leukemia (CML). The … obtained during dasatinib
treatment can be used successfully. … The fertilization rate, pregnancy rate, live birth rate, and …

Health-related quality of life of patients with chronic myeloid leukemia as measured by patient-reported outcomes: current state and future directions

KL Schoenbeck, KE Flynn - Current hematologic malignancy reports, 2021 - Springer
… The success of second-generation TKIs in randomized … on HRQOL domains while taking
dasatinib than imatinib compared to … While the use of TKIs in men is not associated with birth

Low-dose dasatinib (50 mg daily) frontline therapy in newly diagnosed chronic phase chronic myeloid leukemia: 5-year follow-up results

G Gener-Ricos, FG Haddad, K Sasaki, GC Issa… - … Myeloma and Leukemia, 2023 - Elsevier
… The fourth patient became unintentionally pregnant and had … After delivery of a healthy baby,
dasatinib was resumed at 50 … was taken off the study and switched to bosutinib successfully