… has been successfully inhibited at dasatinib nanomolar concentrations (30, 31). The effectiveness
of dasatinib … Dasatinib is delivered by mouth and ranges from 0.5 to 6 hours after oral …

… was reported only in patients receiving dasatinib (10%). After … , and delivery during treatment
with TKIs. In contrast, female … , and successfully complete a healthy pregnancy to term. …

… successful pregnancies were observed in dasatinib-treated CML … successful pregnancies
in a woman with chronic myeloid … Successful management of chronic myeloid leukemia with …

… count is successfully reduced by cytoreductive therapy. … of 258 patients treated with dasatinib
and 0 of 258 patients treated … with ET became pregnant and the live birth rate was 75.9%. A …

… successful small molecule inhibitor so far is imatinib, which is a TKI used in the treatment of
chronic myeloid leukemia (… on 51 patients who received dasatinib describes that dasatinib …

… The successful treatment for acute myeloid leukemia is in its … with those in the chronic phase
who used dasatinib (another … pregnant women, specifically with chronic myeloid leukemia, …

… Introduction: CML is one of the successful stories in oncology. … in DMR due to intolerance
or pregnancy were included. Most of our … TKI (imatinib, bosutinib, dasatinib, or nilotinib at their …

… to treatment, which is critical for the success of therapy. … Patients can then be restarted on
lower doses of dasatinib (20–… discontinued after pregnancy documented), 12 had birth defects, …

… for the treatment of chronic myelogenous leukemia (CML) [… Although the effect of dasatinib
on male fertility have not … to have successful outcomes, imatinib treatment during pregnancy …

… Chronic myeloid leukemia (CML) is a clonal … (eg using dasatinib 50 mg daily; or even 20
mg daily in patients 70 years … discontinued after pregnancy documented), 12 had birth defects, …