Conditional, inducible gene silencing in dopamine neurons reveals a sex-specific role for Rit2 GTPase in acute cocaine response and striatal function
CG Sweeney, PJ Kearney, RR Fagan… - …, 2020 - nature.com
… the first to acheive AAV-mediated, conditional and inducible … in TH + midbrain neurons,
and (+)dox diet suppressed GFP … reward, whereas D2 + MSN activation is thought to mediate …
and (+)dox diet suppressed GFP … reward, whereas D2 + MSN activation is thought to mediate …
[PDF][PDF] Dopamine-evoked synaptic regulation in the nucleus accumbens requires astrocyte activity
M Corkrum, A Covelo, J Lines, L Bellocchio… - Neuron, 2020 - cell.com
… astrocytes as active components of dopaminergic signaling and the brain reward system. …
ATP/adenosine is the gliotransmitter that mediates the dopamine-induced synaptic regulation. …
ATP/adenosine is the gliotransmitter that mediates the dopamine-induced synaptic regulation. …
Ventral pallidum GABA neurons mediate motivation underlying risky choice
MR Farrell, JSD Esteban, L Faget… - Journal of …, 2021 - Soc Neuroscience
… neurons mediate instrumental seeking of high-value rewards, but not necessarily consumption
of the reward … , we speculate that suppressing VP GABA neuron activity might be useful …
of the reward … , we speculate that suppressing VP GABA neuron activity might be useful …
[HTML][HTML] Ventral pallidal regulation of motivated behaviors and reinforcement
C Soares-Cunha, JA Heinsbroek - Frontiers in Neural Circuits, 2023 - frontiersin.org
… reward coding and prediction error processing than neurons … of behavioral responding for
the removal of that stimulus (eg, … Thus, VP GABA and VP Glu neurons mediate positive and …
the removal of that stimulus (eg, … Thus, VP GABA and VP Glu neurons mediate positive and …
Lateral hypothalamic area neuropeptides modulate ventral tegmental area dopamine neurons and feeding
P Perez-Bonilla, K Santiago-Colon, GM Leinninger - Physiology & behavior, 2020 - Elsevier
… to VTA DA neuronal mechanisms to promote or suppress feeding, … DA neurons that primarily
mediate orexigenic responses vs. those that constrain feeding or other rewards and mediate …
mediate orexigenic responses vs. those that constrain feeding or other rewards and mediate …
PRC2-mediated repression is essential to maintain identity and function of differentiated dopaminergic and serotonergic neurons
K Toskas, B Yaghmaeian-Salmani, O Skiteva… - Science …, 2022 - science.org
… impairment of dopaminergic and serotonergic neuronal function, … to loss of PRC2 repression
in dopamine neurons of the … examined whether perturbation in the reward system of 8-month…
in dopamine neurons of the … examined whether perturbation in the reward system of 8-month…
[PDF][PDF] Nigrostriatal dopamine signals sequence-specific action-outcome prediction errors
… This dopamine suppression generalized to food rewards … a bona fide prediction-error
signal mediated by expectation. … activity of midbrain dopamine neurons following reward-predictive …
signal mediated by expectation. … activity of midbrain dopamine neurons following reward-predictive …
[PDF][PDF] Dopamine errors drive excitatory and inhibitory components of backward conditioning in an outcome-specific manner
… dopamine neurons are ‘‘specialized’’ for anticipatory reward … the magazine to consume the
rewards. Here, green light was … 2.5 s to suppress phasic firing of dopamine neurons without …
rewards. Here, green light was … 2.5 s to suppress phasic firing of dopamine neurons without …
[HTML][HTML] Nesfatin-1 decreases the motivational and rewarding value of food
… activation of VTA dopamine neurons, we employed the 2-… preference due to a selective
suppression of sucrose intake, … for pinpointing the brain areas mediating nesfatin-1s effects. In fact…
suppression of sucrose intake, … for pinpointing the brain areas mediating nesfatin-1s effects. In fact…
The indirect pathway of the basal ganglia promotes transient punishment but not motor suppression
… encode information related to both movement and reward.Although the GPe is an obligate
… that the motor-suppressing effects of A2A-SPNs are not mediated through the GPe and are …
… that the motor-suppressing effects of A2A-SPNs are not mediated through the GPe and are …