Addictive drugs modify neurogenesis, synaptogenesis and synaptic plasticity to impair memory formation through neurotransmitter imbalances and signaling …

A Rezayof, Z Ghasemzadeh, OH Sahafi - Neurochemistry International, 2023 - Elsevier
… The mesocorticolimbic brain regions are involved in reward-… neurotransmitter receptor-mediated
signaling pathways. The … protein (CREB) impair reward-related memory formation …

Direct evidence that the brain reward system is involved in the control of scratching behaviors induced by acute and chronic itch

T Setsu, Y Hamada, D Oikawa, T Mori, Y Ishiuji… - Biochemical and …, 2021 - Elsevier
… system by the DREADD technique, we found that the suppression of mesolimbic dopaminergic
neurons by CNO (3 mg/kg) significantly reduced the number and duration of scratching …

Mechanism of opioid addiction and its intervention therapy: Focusing on the reward circuitry and mu‐opioid receptor

JJ Zhang, CG Song, JM Dai, L Li, XM Yang… - MedComm, 2022 - Wiley Online Library
… The underlying mechanism of MOR-mediated opioid rewarding … of MORs-mediated opioid
reward and withdrawal. The … DA neurons, 160 and intravenous morphine could suppress

The neural basis of sugar preference

WW Liu, DV Bohórquez - Nature Reviews Neuroscience, 2022 - nature.com
… to mediate subconscious aspects of food reward and selection … ventral striatal dopamine
release and suppressing gut-mediatedneurons, specifically mesolimbic dopaminergic neurons, …

Serotonin, food intake, and obesity

KA van Galen, KW Ter Horst, MJ Serlie - Obesity Reviews, 2021 - Wiley Online Library
… facilitates the ability to suppress food intake when homeostatic … Overall, it has been shown
that reward and homeostatic … of central serotonin-mediated regulation of food intake as well …

Endogenous opioid system modulates conditioned cocaine reward in a sex‐dependent manner

K Matsumura, A Nicot, IB Choi, M Asokan… - Addiction …, 2023 - Wiley Online Library
… enkephalin-mediated disinhibition of dopamine neurons in the … disinhibit striatal dopamine
release by suppressing GABA … onto ventral tegmental area dopamine neurons. Mice with a …

The circadian neurobiology of reward

I Olejniczak, K Begemann, I Wilhelm… - Acta …, 2023 - Wiley Online Library
… Impaired repression by NR1D1 would increase TH … in reward-related brain areas such as
the VTA and the NAc. Hedonic food intake rhythms are mediated by dopaminergic neurons in …

[PDF][PDF] Striatal dopamine explains novelty-induced behavioral dynamics and individual variability in threat prediction

K Akiti, I Tsutsui-Kimura, Y Xie, A Mathis, JE Markowitz… - Neuron, 2022 - cell.com
… ‘‘shaping bonus’’) and a threat prediction that is learned through dopamine-mediated threat
… ideas to model approach suppression by incorporating a shaping bonus and uncertainty into …

Stress-induced plasticity of a CRH/GABA projection disrupts reward behaviors in mice

MT Birnie, AK Short, GB de Carvalho… - Nature …, 2023 - nature.com
reward behavior. We then establish that this projection mediates deficits in adult reward-…
or both neuromodulators, might mediate suppressed reward behaviors often observed after …

Visualization of learning-induced synaptic plasticity in output neurons of the Drosophila mushroom body γ-lobe

CE Hancock, V Rostami, EY Rachad, SH Deimel… - Scientific Reports, 2022 - nature.com
… -dopaminergic neuron (DAN)-mushroom body output neuron … that approach-mediating
MBONs would be suppressed in … by distinct subsets of DANs mediating reward or punishment, …