Prefrontal cortical and nucleus accumbens contributions to discriminative conditioned suppression of reward-seeking

PT Piantadosi, DCM Yeates, SB Floresco - Learning & Memory, 2020 - learnmem.cshlp.org
… These findings extend our knowledge of cortico-striatal circuits mediating flexible reward-seeking,
identifying prefrontal input to the medial NAc as a critical component of such a network…

[PDF][PDF] Synergy of distinct dopamine projection populations in behavioral reinforcement

G Heymann, YS Jo, KL Reichard, N McFarland… - Neuron, 2020 - cell.com
reward association and motivation. It remains unclear whether there are distinct
dopamine populations to mediate … Selective elimination of dopamine synthesis in Crhr1-expressing …

[HTML][HTML] Seeking motivation and reward: Roles of dopamine, hippocampus, and supramammillo-septal pathway

AJ Kesner, CB Calva, S Ikemoto - Progress in neurobiology, 2022 - Elsevier
… Reinforcement learning and goal-seeking behavior are thought to be mediated by
midbrain dopamine neurons. However, little is known about neural substrates of curiosity and …

[HTML][HTML] Corticosterone attenuates reward-seeking behavior and increases anxiety via D2 receptor signaling in ventral tegmental area dopamine neurons

B Peng, Q Xu, J Liu, S Guo, SL Borgland… - Journal of …, 2021 - Soc Neuroscience
… treatment suppresses excitability and synaptic transmission onto VTA dopamine neurons. …
Together, CORT-induced neuronal disruptions in a key region mediating reward-seeking …

[PDF][PDF] Nucleus accumbens cell type-and input-specific suppression of unproductive reward seeking

CK Lafferty, AK Yang, JA Mendoza, JP Britt - Cell Reports, 2020 - cell.com
… or D2 Neurons Increases Unproductive Reward Seeking We … neuron activity would interfere
with behavioral suppression, … neurons appears to be critical for NAc-mediated suppression

[HTML][HTML] Ventral tegmental area GABA neurons mediate stress-induced blunted reward-seeking in mice

DC Lowes, LA Chamberlin, LN Kretsge, ES Holt… - Nature …, 2021 - nature.com
… Surprisingly, while previous studies on blunted reward-seeking focused on dopamine (DA) …
DA, neurons mediate stress-induced blunted reward-seeking. Inhibiting VTA GABA neurons

Dopamine signaling in the nucleus accumbens core mediates latent inhibition

MG Kutlu, JE Zachry, PR Melugin, J Tat, S Cajigas… - Nature …, 2022 - nature.com
… were used to test the effect of photostimulation of dopamine neurons in the VTA on latent
inhibition in an appetitive procedure using food rewards (Extended Data Fig. 10). These rats …

Serotonergic regulation of the dopaminergic system: Implications for reward-related functions

E Courtiol, EC Menezes, CM Teixeira - Neuroscience & Biobehavioral …, 2021 - Elsevier
… From these studies, it appears that activation of this pathway can lead to reinforcement
learning mediated through the excitation of dopaminergic neurons by serotonergic neurons co-…

[HTML][HTML] Stress and the dopaminergic reward system

JH Baik - Experimental & molecular medicine, 2020 - nature.com
… Stress affects dopamine levels and dopaminergic neuronal … the postsynaptic modulation
mediating reward-directed and … compared to the suppression of VTA DA neuronal activity after …

Central oxytocin signaling inhibits food reward-motivated behaviors and VTA dopamine responses to food-predictive cues in male rats

CM Liu, TM Hsu, AN Suarez, KS Subramanian… - Hormones and …, 2020 - Elsevier
mediating these behavioral outcomes, we utilized in vivo fiber photometry in ventral tegmental
area (VTA) dopamine neuronssuppressed food (sucrose) cue-evoked dopamine neuron