… surfactant metabolism are a diverse group of rare and complex respiratory diseases. Our case
illustrates an early diagnosis of surfactant protein B deficiency … to be the future therapy but …

… Surfactant proteins, such as surfactant protein B and surfactant protein C, contribute to … In
terms of prospective treatments, recent studies in murine models have also shown encouraging …

… discuss these diagnostic tools from a pathophysiological and multi-disciplinary perspective,
… ,[39] due to a relative surfactant dilution or under-expression of surfactant proteins.[93] The …

… and surfactant protein, IGF-2 deficiency was shown to result in decreased airspace
formation in fetal lungs, less alveolar separation, decreased SP-A expression, increased SP-B …

… the most promising aims for future development. Scientists have … of specific proteins, called
surfactant protein (SP)-A, -B, -C … of RDS antenatally, 9 need for intubation and surfactant early …

… expression of surfactant proteins (surfactant protein A [SPA], surfactant protein B, and pro-surfactant
protein C) in … Future directions in this research area will be to study the genotype of …

… the endogenous surfactant protein levels of the fetal lung, including SP-D. The expression
of SP-D in the fetal lung … may finally lead to the testing of this novel agent in the near future. …

… in the antenatal period and to able to treat it, various methods for antenatal lung maturity …
For this intention, future refinement of this work may include the increase of the amount of …

… SP-B deficiency is the c.397delCinsGAA (previously known as 121ins2) mutation which occurs
in 70% of patients with surfactant protein B deficiency -… in a multidisciplinary perspective. …

… The amount of surfactant present in fetal lungs increases steadily … Surfactant protein B (SP-B)
is a hydrophobic protein … option for patients with SP-B deficiency in the future, newborns are …