Three-dimensional liver models: State of the art and their application for hepatotoxicity evaluation
X Zhang, T Jiang, D Chen, Q Wang… - Critical Reviews in …, 2020 - Taylor & Francis
… hepatocytes, stem cell derived hepatocyte like cells, and immortalized hepatic cell lines as
cell resources for model reconstruction. Primary hepatocytes … Since then, novel methods for …
cell resources for model reconstruction. Primary hepatocytes … Since then, novel methods for …
Current research trends in the application of in vitro three-dimensional models of liver cells
C Yun, SH Kim, YS Jung - Pharmaceutics, 2022 - mdpi.com
… , are known to be biodegradable. These … survival capacity and high albumin production
[89,90]. As such, many studies have been conducted recently to promote the function of liver cells …
[89,90]. As such, many studies have been conducted recently to promote the function of liver cells …
Development of a 3D porous chitosan/gelatin liver scaffold for a bioartificial liver device
YT Hou, CC Hsu - Journal of bioscience and bioengineering, 2020 - Elsevier
… In this study, a three-dimensional (3D) liver scaffold for in … reports, hepatocytes that are
seeded in porous three-dimensional (3D) … Third, they have adequate biodegradability, sufficient …
seeded in porous three-dimensional (3D) … Third, they have adequate biodegradability, sufficient …
3D scaffold-free microlivers with drug metabolic function generated by lineage-reprogrammed hepatocytes from human fibroblasts
… Three-dimensional (3D) scaffoldless microliver spheroids … hepatocyte-like cells can survive
and remain functional for 30 … , and cytokines in a biodegradable microsphere to reduce the …
and remain functional for 30 … , and cytokines in a biodegradable microsphere to reduce the …
Highly efficient fabrication of functional hepatocyte spheroids by a magnetic system for the rescue of acute liver failure
… prolongs the animal survival, ameliorates inflammation, and … microwell arrays in a three-dimensional
manner and aggregated into … a novel strategy for efficient production of functional …
manner and aggregated into … a novel strategy for efficient production of functional …
Fabrication and evaluation of modified poly (ethylene terephthalate) microfibrous scaffolds for hepatocyte growth and functionality maintenance
… three-dimensional (3D) hepatocyte culture scaffolds, since they can well mimic the hepatocyte
… is a commercial cost-effective and non-biodegradable substrate with proper 3D structure, …
… is a commercial cost-effective and non-biodegradable substrate with proper 3D structure, …
Biomaterial-based cell delivery strategies to promote liver regeneration
M Ali, SL Payne - Biomaterials Research, 2021 - spj.science.org
… with novel strategies that recapitulate liver organization and … capable of differentiating into
functional hepatocyte-like cells when … of collagen, is biodegradable, inexpensive and easy to …
functional hepatocyte-like cells when … of collagen, is biodegradable, inexpensive and easy to …
[HTML][HTML] Regulated differentiation of stem cells into an artificial 3D liver as a transplantable source
F Chen, H Wang, J Xiao - Clinical and Molecular Hepatology, 2020 - ncbi.nlm.nih.gov
… liver transplantation therapy, artificial three-dimensional (3D) liver … could support hepatocyte
survival and function with minimal … However, synthetic biodegradable polymers have poor …
survival and function with minimal … However, synthetic biodegradable polymers have poor …
Establishing a 3D in vitro hepatic model mimicking physiologically relevant to in vivo state
… Three-dimensional (3D) bioprinting is a promising … and mainly consists of hepatocytes, which
comprise approximately … critical role in cell adhesion, biocompatibility and biodegradability […
comprise approximately … critical role in cell adhesion, biocompatibility and biodegradability […
Liver tissue engineering as an emerging alternative for liver disease treatment
… hepatocyte-like cells (HLCs) seeded on a three-dimensional (3D) scaffold, which can maintain
the viability and functional … network and structure through novel methods and materials. …
the viability and functional … network and structure through novel methods and materials. …