Extracellular Vesicle Formation in Cryptococcus deuterogattii Impacts Fungal Virulence and Requires the NOP16 Gene

RF Castelli, A Pereira, L Honorato, A Valdez… - Infection and …, 2022 - Am Soc Microbiol
… We also tested melanin formation as another cryptococcal … incubated at 60C for 48 h until
complete polymerization of the … the decision to publish, or preparation of the manuscript. The …

[HTML][HTML] The Host Immune Response to Scedosporium/Lomentospora

I Buldain, L Martin-Souto, A Antoran, M Areitio… - Journal of Fungi, 2021 - mdpi.com
… After recognition, cytokine synthesis and antifungal activity of … Among the antigens recognized
by the sera of mice infected … of melanin over time and suggesting melanin polymerization. …

Melanization in Candida auris: A Characterization and Investigation of Its Mechanism

NJL Mudrak - 2022 - jscholarship.library.jhu.edu
… through a laccase enzyme, and once polymerized, the … For instance, the fungal pathogen
Cryptococcus neoformans, … mechanism of melanin synthesis and on potential drivers of C. auris…

Characterization of the WEE1 Homologues and the Investigation of Factors Promoting Cellular Enlargement in Cryptococcus Neoformans

RJ Colón Reyes - 2022 - tigerprints.clemson.edu
… Metabolites interferes with RNA biosynthesis, preventing the … polymerization of phenolic
and/or indole compounds. … and melanin production, it is the main form found in infected tissue …

[HTML][HTML] Ultrastructural Study of Cryptococcus neoformans Surface During Budding Events

GRS Araújo, CL Alcantara, N Rodrigues… - Frontiers in …, 2021 - frontiersin.org
… , conjugation, cell wall synthesis and iron acquisition. … , post-fixation and resin polymerization
times, mainly because … The polymerization step was carried out for 48 h in an oven …

[HTML][HTML] Targeting Melanin in Melanoma with Radionuclide Therapy

KJH Allen, ME Malo, R Jiao, E Dadachova - International Journal of …, 2022 - mdpi.com
… [70] reported synthesis, in vitro and in vivo evaluation in mouse models of a novel ( 123 / …
amelanotic melanoma-bearing mice, attesting to their high specificity for melanin (Figure 4). …

Inhibiting DHN- and DOPA-melanin biosynthesis pathway increased the therapeutic value of itraconazole in Madurella mycetomatis infected Galleria mellonella

W Lim, M Konings, F Parel, K Eadie, N Strepis… - Medical …, 2022 - academic.oup.com
Cryptococcus neoformans produces melanin via oxidation of L-… The DOPA-melanin
biosynthesis pathway proposed in insects … auto-polymerization of L-dopa in the fungus …

Melanin Pigments as Antibacterial Agents

TR Eliato - 2022 - search.proquest.com
… (DHN) is synthesized and polymerized to form allomelanin … organs of rats after treatment
compared to the control rats. … against both Cryptococcus neoformans and Cryptococcosis gattii, …

[HTML][HTML] Influence of pathogen carbon metabolism on interactions with host immunity

HP Berguson, LW Caulfield, MS Price - … in Cellular and Infection …, 2022 - frontiersin.org
Cryptococcus neoformans is a ubiquitous opportunistic fungal pathogen typically causing …
Synthesis of capsule polysaccharide involves the polymerization of simple sugars into an …

Recent progress in multifunctional conjugated polymer nanomaterial-based synergistic combination phototherapy for microbial infection theranostics

P Manivasagan, J Kim, ES Jang - Coordination Chemistry Reviews, 2022 - Elsevier
Microbial infection is a critical public health problem, owing to its strong infectivity and high
risk of mortality. Multi-antibiotic resistant pathogens reduce the efficacy of commercial …