… targeting SARS-CoV-2 receptor binding domain to mucosal microfold cells and adjuvanted with TLR3 agonist Riboxxim™ elicits strong antibody and T-cell responses …
D Horvath, N Temperton, M Mayora-Neto… - Scientific Reports, 2023 - nature.com
… A combination vaccine with M-cell targeted recombinant HA1 … We used the novel synthetic
double stranded RNA (dsRNA) … antigen-presenting cells (APC), including dendritic cells, and …
double stranded RNA (dsRNA) … antigen-presenting cells (APC), including dendritic cells, and …
Genetic fusion of CCL11 to antigens enhances antigenicity in nucleic acid vaccines and eradicates tumor mass through optimizing T-cell response
H Qi, Z Sun, T Gao, Y Yao, Y Wang, W Li, X Wang… - Molecular Cancer, 2024 - Springer
… by antigen-presenting cells (APCs) to trigger T helper cell or … expressed fusion proteins after
synthesis, we obtained plasmids … of specific CD8 + T cells and the antitumor responses were …
synthesis, we obtained plasmids … of specific CD8 + T cells and the antitumor responses were …
[HTML][HTML] Nanodrugs targeting T cells in tumor therapy
M Haist, V Mailänder, M Bros - Frontiers in Immunology, 2022 - frontiersin.org
… cells directly or to address antigen presenting cells (APC) like dendritic cells (DC) in order to
elicit tumor antigen-specific T … are attached to nano-sized beads, termed artificial (a)APC (9). …
elicit tumor antigen-specific T … are attached to nano-sized beads, termed artificial (a)APC (9). …
[HTML][HTML] The era of cytotoxic CD4 T cells
M Cenerenti, M Saillard, P Romero… - Frontiers in …, 2022 - frontiersin.org
… Indeed, CD26 high CD4 T cells elicit potent immunity against … or induced by long synthetic
peptide immunization in … to be confined to antigen-presenting cells and phagocytes. However, …
peptide immunization in … to be confined to antigen-presenting cells and phagocytes. However, …
Nanomedicine for T‐Cell Mediated Immunotherapy
… by antigen presenting cells (APCs),[7] which in turn elicit antigen … The encapsulated synthetic
mRNA could encode … trend,[157] with T celltargeted therapy being a specific treatment for …
mRNA could encode … trend,[157] with T celltargeted therapy being a specific treatment for …
… proteins-encapsulated nanovaccine enhances cancer immunotherapy and prevention by provoking antigen-specific cellular immunity via the dendritic cell-targeted …
X Luo, X Chen, R Ma, Z Fu, Z Liu, Q Su, H Fu… - Chemical Engineering …, 2024 - Elsevier
… by antigen presenting cells (APCs), especially dendritic cells (… that can elicit a robust antitumor
immune response is still … humidity of 40–70 %, and artificial light of 12 h dark-light cycle. …
immune response is still … humidity of 40–70 %, and artificial light of 12 h dark-light cycle. …
Direct in vivo CAR T cell engineering
… retargeting of T cells with synthetic receptors CAR T cell … or damaged cells that elicit a
type I interferon response (ie, … T cell-targeted viral vectors can deliver CAR genetic cargo in …
type I interferon response (ie, … T cell-targeted viral vectors can deliver CAR genetic cargo in …
Liposome Vaccine for Active Regulation of Cellular and Humoral Immunity
… cross-presentation ability of antigen-presenting cells (APCs) for … Synthetic
oligodeoxynucleotides containing CpG motifs (CpG … vaccines might elicit protective responses by …
oligodeoxynucleotides containing CpG motifs (CpG … vaccines might elicit protective responses by …
Targeting neoantigens to APC-surface molecules improves the immunogenicity and anti-tumor efficacy of a DNA cancer vaccine
M Barrio-Calvo, SV Kofoed, SC Holste… - Frontiers in …, 2023 - frontiersin.org
… how the addition of an antigen-presenting cell (APC) binding … elicit neoepitope-specific
CD8+ and CD4+ T-cell responses … per well were stimulated with synthetic neopeptide pools …
CD8+ and CD4+ T-cell responses … per well were stimulated with synthetic neopeptide pools …
Nanotechnology-based multifunctional vaccines for cancer immunotherapy
X Xie, T Song, Y Feng, H Zhang, G Yang, C Wu… - Chemical Engineering …, 2022 - Elsevier
… antigen-presenting cells and induce specific antitumor … Another study reported a lymphatic
DC-targeted artificial … low immunogenicity and cannot elicit a strong T cell response in vivo, …
DC-targeted artificial … low immunogenicity and cannot elicit a strong T cell response in vivo, …