Lipo-based vaccines as an approach to target dendritic cells for induction of T-and iNKT cell responses
DA Stolk, A De Haas, J Vree, S Duinkerken… - Frontiers in …, 2020 - frontiersin.org
… vaccine containing palmitoylated synthetic long peptides (… is taken up by skin antigen
presenting cells (APC) and results … with neoepitopes might elicit stronger anti-tumor responses …
presenting cells (APC) and results … with neoepitopes might elicit stronger anti-tumor responses …
[HTML][HTML] Nanomaterial-based delivery vehicles for therapeutic cancer vaccine development
J Liang, X Zhao - Cancer Biology & Medicine, 2021 - ncbi.nlm.nih.gov
… these specific antigens to antigen-presenting cells (APCs) 24 … Notably, DC-targeted and
CD8 + T cell-targeted nanovectors … + T cell activation, synthesized polymers based on artificial …
CD8 + T cell-targeted nanovectors … + T cell activation, synthesized polymers based on artificial …
Multi-functional nanocomplex codelivery of Trp2 and R837 to activate melanoma-specific immunity
Z Ji, Z Tan, M Li, J Tao, E Guan, J Du, Y Hu - International Journal of …, 2020 - Elsevier
… of Trp2 and R837 into antigen-presenting cells (APCs). R837 … usually elicit weak and short-lived
immune responses owing … The inclusion of R837 in man-CD and synthesis of WT altered …
immune responses owing … The inclusion of R837 in man-CD and synthesis of WT altered …
Recombinant programmed cell death protein 1 functions as an immune check point blockade and enhances anti-cancer immunity
J Hwang, EK An, W Zhang, HB Park, SJ Kim, D Yadav… - Biomaterials, 2022 - Elsevier
… Therefore, cancer cell-targeted therapies are currently … challenge by piHNPs elicited a
protective effect against the … apoptotic cells may contribute to the induction of antigen-presenting …
protective effect against the … apoptotic cells may contribute to the induction of antigen-presenting …
Harnessing self-assembling peptide nanofibers to prime robust tumor-specific CD8 T cell responses in mice
… in terms of their uptake by antigen-presenting cells (APCs), … owing to their relative ease of
synthesis in tandem with target epitope … platform to elicit specific CD8+ T cells against epitopes …
synthesis in tandem with target epitope … platform to elicit specific CD8+ T cells against epitopes …
Apoptotic body-mediated intracellular delivery strategy for enhanced STING activation and improved tumor immunogenicity
P Bao, ZT Zheng, JJ Ye, XZ Zhang - Nano Letters, 2022 - ACS Publications
… are readily phagocytosed by antigen-presenting cells (APCs)… , lacking exploration in the
role of tumor-cell-targeted STING … immune response, eliciting systemic antitumor immunity …
role of tumor-cell-targeted STING … immune response, eliciting systemic antitumor immunity …
Recent advance in nanomaterials for cancer immunotherapy
Y Hou, Y Liu, C Tang, Y Tan, X Zheng, Y Deng… - Chemical Engineering …, 2022 - Elsevier
… and promotes the activity of antigen presenting cells (APC) and cytotoxic T cells (CTL) at the
… to provoke the anti-tumor immune response [165]. aAPCs: artificial antigen-presenting cells. …
… to provoke the anti-tumor immune response [165]. aAPCs: artificial antigen-presenting cells. …
In Vivo T Cell-Targeting Nanoparticle Drug Delivery Systems: Considerations for Rational Design
… -II on antigen-presenting cells, such as dendritic cells, and … Additionally, we provide an
overview of T cell-targeted … First, upon entering the bloodstream, synthetic nanoparticles will …
overview of T cell-targeted … First, upon entering the bloodstream, synthetic nanoparticles will …
[HTML][HTML] Controlling timing and location in vaccines
… , or from synthetic nucleic … response: First, antigens must be identified that present a molecular
structure to the immune system capable of eliciting protective antibody or T cell responses. …
structure to the immune system capable of eliciting protective antibody or T cell responses. …
Targeting dendritic cells for antigen delivery in vaccine design
… to antigen-presenting cells and stimulate immune responses. … were able to induce antitumor
immune responses [150], … conjugated vaccine elicited robust cellular immune responses and …
immune responses [150], … conjugated vaccine elicited robust cellular immune responses and …