Dendritic cell-based vaccine: the state-of-the-art vaccine platform for COVID-19 management
… antigen-presenting cells that play a vital role in the process and modulation of the immune
system’s innate and adaptive arms. DC elicits an antigen-specific immune response … synthesis …
system’s innate and adaptive arms. DC elicits an antigen-specific immune response … synthesis …
Materials engineering strategies for cancer vaccine adjuvant development
… of tumor antigens in antigen-presenting cells (APCs) followed by … and minimize potential
toxic side effects; (2) obtaining synthetic … Thus, it is necessary to design T cell-targeted delivery …
toxic side effects; (2) obtaining synthetic … Thus, it is necessary to design T cell-targeted delivery …
The current landscape of CAR T-cell therapy for solid tumors: Mechanisms, research progress, challenges, and counterstrategies
A Daei Sorkhabi, L Mohamed Khosroshahi… - Frontiers in …, 2023 - frontiersin.org
… IL-2 synthesis to turn on T-cells and deter apoptosis (13). Intensified … Although the former
can provoke innate immune responses … in the lack of the CAR T-cell targeted antigen or CAR …
can provoke innate immune responses … in the lack of the CAR T-cell targeted antigen or CAR …
Nanotechnologies in Delivery of DNA and mRNA Vaccines to the Nasal and Pulmonary Mucosa
… in specific antigen-presenting cells (APCs) or epithelial cells (… as that in mouse studies to
elicit significant clinical benefits [3]. … cells results in low antigen synthesis, limiting the protective …
elicit significant clinical benefits [3]. … cells results in low antigen synthesis, limiting the protective …
Regulation of Antigen‐Specific Immunotherapy with Nanomaterials
… heterogeneous population of antigenpresenting cells (APCs).[… fabrication of β-cell-targeted
Ac4ManNAz-encapsulated PLGA … a) A diagram illustrating the synthesis of Man-MnO2@OVA …
Ac4ManNAz-encapsulated PLGA … a) A diagram illustrating the synthesis of Man-MnO2@OVA …
SMART-lipid nanoparticles enabled mRNA vaccine elicits cross-reactive humoral responses against the omicron sub-variants
G Mahalingam, HK Rachamalla, P Arjunan… - Molecular Therapy, 2024 - cell.com
… potent antigen-presenting cells and contribute to stimulating T … efficient and long-lasting
protective T cell immunity. Furthermore, … mRNA synthesis, we replaced 100% of UTP with me1J 5 …
protective T cell immunity. Furthermore, … mRNA synthesis, we replaced 100% of UTP with me1J 5 …
Immune cell-derived extracellular vesicles–new strategies in cancer immunotherapy
P Yang, Y Peng, Y Feng, Z Xu, P Feng, J Cao… - Frontiers in …, 2021 - frontiersin.org
… TNF-α and IFN-γ are crucial for nitric oxide (NO) synthesis, which also facilitates vesicle-… I
molecules on antigen-presenting cells and presented to T cells to activate antitumor responses. …
molecules on antigen-presenting cells and presented to T cells to activate antitumor responses. …
Glycan-costumed virus-like particles promote type 1 anti-tumor immunity
… As professional antigen-presenting cells (APCs), DCs internalize … The immune protection
observed following therapeutic … Robust immune responses elicited by a fully synthetic three-…
observed following therapeutic … Robust immune responses elicited by a fully synthetic three-…
Targeting tumor-infiltrating tregs for improved antitumor responses
D Qin, Y Zhang, P Shu, Y Lei, X Li, Y Wang - Frontiers in Immunology, 2024 - frontiersin.org
… activity of effector T cells and antigen-presenting cells, plays … glycolysis rates, and fatty
acid synthesis compared to Tconvs, … in the TME, indirectly protecting Treg cells from ATP-triggered …
acid synthesis compared to Tconvs, … in the TME, indirectly protecting Treg cells from ATP-triggered …
Radiotherapy remodels the tumor microenvironment for enhancing immunotherapeutic sensitivity
S Liu, W Wang, S Hu, B Jia, B Tuo, H Sun… - Cell Death & …, 2023 - nature.com
… complex (MHC) on antigen-presenting cells (APCs) [7]. The … the ability of T cells to elicit
anti-tumor responses. Radiation … in T and NK cells, thereby reducing IFN-γ synthesis and favoring …
anti-tumor responses. Radiation … in T and NK cells, thereby reducing IFN-γ synthesis and favoring …