Immune and inflammation in acute coronary syndrome: molecular mechanisms and therapeutic implications

H Wang, Z Liu, J Shao, L Lin, M Jiang… - … of Immunology …, 2020 - Wiley Online Library
… innate immune system and triggers the immune cell … T cell differentiation and promoting
downstream proinflammatory reactions [19, 38]. IL-6 mobilizes hepatocytes to synthesize acute

Differential immunological signature at the culprit site distinguishes acute coronary syndrome with intact from acute coronary syndrome with ruptured fibrous cap …

DM Leistner, N Kränkel, D Meteva… - European Heart …, 2020 - academic.oup.com
… The different immune signatures identified in this … + T-cell subpopulations (B) as well as
increased T-cell effector molecules at the culprit site distinguishing acute coronary syndromes

[HTML][HTML] The role of natural killer (NK) cells in acute coronary syndrome: A comprehensive review

M Kumrić, T Tičinović Kurir, JA Borovac, J Božić - Biomolecules, 2020 - mdpi.com
… CD28-CD57+ T cell number, a T cell subset which suppresses … cells has been known to
trigger an immune response [59]. Cell-… interaction of immune cells in both coronary plaques and …

Pro-inflammatory cytokines in acute coronary syndromes

K Mourouzis, E Oikonomou, G Siasos… - Current …, 2020 - ingentaconnect.com
… exert cardioprotective effects and regulates immune maturation and function of dendritic
cells in ACS patients [329, 330]. There is also evidence that the amplification of the T-cell/IFN-γ/…

[HTML][HTML] The regulatory role of T cell responses in cardiac remodeling following myocardial infarction

T Kino, M Khan, S Mohsin - International Journal of Molecular Sciences, 2020 - mdpi.com
… current status of immune cells within the heart post-MI with an emphasis on T cell mediated
… After surviving from acute coronary syndrome (ACS), optimal medical therapy (OMT) is a …

… index is associated with vulnerable plaque components and local immune‐inflammatory activation in patients with non‐ST elevation acute coronary syndrome

JT Sun, XC Sheng, Q Feng, Y Yin, Z Li… - Journal of the …, 2022 - Am Heart Assoc
… related to acute coronary syndrome (ACS) development. Long‐term activation of the immune‐…
For quantification of the local T cell subset and immune‐inflammatory mediators, 20 mL of …

Innate and adaptive immune cell subsets as risk factors for coronary heart disease in two population-based cohorts

NC Olson, CM Sitlani, MF Doyle, SA Huber, AL Landay… - Atherosclerosis, 2020 - Elsevier
T cell subsets with the future occurrence of MI or angina. Associations of each of the 34 immune
… the peripheral blood of patients with coronary artery disease (CAD) and acute coronary

A unique population of regulatory T cells in heart potentiates cardiac protection from myocardial infarction

N Xia, Y Lu, M Gu, N Li, M Liu, J Jiao, Z Zhu, J Li, D Li… - Circulation, 2020 - Am Heart Assoc
… Photoconversion, parabiosis, single-cell T-cell receptor … Tregs for cardioprotection in MI
and other cardiac diseases. … the cardiac repair process independent of immune regulation …

[HTML][HTML] RNA sequencing of blood in coronary artery disease: involvement of regulatory T cell imbalance

TA McCaffrey, I Toma, Z Yang, R Katz, J Reiner… - BMC Medical …, 2021 - Springer
… transcripts, possibly consistent with changes in the immune synapse of developing T cells. …
(MTHFD1L) Rs6922269 SNP predicts mortality after acute coronary syndrome [32], and is a …

[HTML][HTML] Adaptive immune disorders in hypertension and heart failure: focusing on T-cell subset activation and clinical implications

A Rai, M Narisawa, P Li, L Piao, Y Li, G Yang… - Journal of …, 2020 - journals.lww.com
… to the progression of cardiac fibrosis and myocardial … inducing T-cell activation. In simple
terms, the presence of systemic dendritic cell elevation in heart failure indicates systemic T-cell