[HTML][HTML] Toll-like receptor 8 agonists improve NK-cell function primarily targeting CD56brightCD16− subset
… by increasing their proliferation, cytokine production and … on dendritic cells, macrophages
and neutrophils cells, activated … TLR8 but not TLR7 agonists increased cytokine production …
and neutrophils cells, activated … TLR8 but not TLR7 agonists increased cytokine production …
Effects of Aire on perforin expression in BMDCs via TLR7/8 and its therapeutic effect on type 1 diabetes
Y Zhang, Y Lu, Y Gao, X Liang, R Zhang… - International …, 2023 - Elsevier
… perforin-deficient BMDCs with CD8 + T cells and evaluated … by inhibiting the production of
IL-12, TNF-α and IL-6 in BMDCs … Here, we developed Aire-modified dendritic cells to treat type …
IL-12, TNF-α and IL-6 in BMDCs … Here, we developed Aire-modified dendritic cells to treat type …
Toll-like receptors 7/8: a paradigm for the manipulation of immunologic reactions for immunotherapy
F Li, B Song, WF Zhou, LJ Chu - Viral Immunology, 2023 - liebertpub.com
… secretion of proinflammatory cytokines by activating immune … may then contribute to
defective virus eradication. These … receptor type 3; DCs, dendritic cells; F4/80, mouse epidermal …
defective virus eradication. These … receptor type 3; DCs, dendritic cells; F4/80, mouse epidermal …
Antiviral response induced by toll-like receptor (TLR) 7/TLR8 activation inhibits human immunodeficiency virus type 1 infection in cord blood macrophages
AJ Pietrobon, FSY Yoshikawa… - The Journal of …, 2022 - academic.oup.com
… that neonatal monocytes, dendritic cells, and macrophages … may not be associated with
deficient expression of the targets … capacity of the TLR7/TLR8 agonist CL097 and its antiviral …
deficient expression of the targets … capacity of the TLR7/TLR8 agonist CL097 and its antiviral …
Integrin αvβ3 Limits Toll-Like Receptor Type I Interferon Production by Plasmacytoid Dendritic Cells and Restricts Autoimmunity
AK Lorant - 2023 - search.proquest.com
… dendritic cells (cytokine production, T cell activation), B cells (autoantibody production), and
plasmacytoid dendritic cells (… integrin resulted in delayed but increased cytokine production. …
plasmacytoid dendritic cells (… integrin resulted in delayed but increased cytokine production. …
X-linked recessive TLR7 deficiency in~ 1% of men under 60 years old with life-threatening COVID-19
T Asano, B Boisson, F Onodi, D Matuozzo… - Science …, 2021 - science.org
… plasmacytoid dendritic cells (pDCs) results in the production … -c, and the production of
IFN-α2 and IL-6 was assessed with … -deficient patients is the impairment of type I IFN production …
IFN-α2 and IL-6 was assessed with … -deficient patients is the impairment of type I IFN production …
Toll-like receptor (TLR) 7 and TLR8 stimulation of mucosal-associated invariant T cells and gamma delta T cells: a role in HIV susceptibility
Z Richard - 2023 - mspace.lib.umanitoba.ca
… PBMCs or monocyte-derived dendritic cells (MDDC) will lead … for TLR9, TLR3, and TLR7/TLR8,
respectively. DNA viruses … Evidence shows that TLR3-deficient mice are susceptible to …
respectively. DNA viruses … Evidence shows that TLR3-deficient mice are susceptible to …
TLR3-Dependent activation of TLR2 endogenous ligands via the MyD88 signaling pathway augments the innate immune response
HS Teixeira, J Zhao, E Kazmierski, DF Kinane… - Cells, 2020 - mdpi.com
… production of inflammatory cytokines and not type I interferon by macrophages and dendritic
cells, the production … poly I:C treatment in MyD88-deficient mice. Taken together, the above …
cells, the production … poly I:C treatment in MyD88-deficient mice. Taken together, the above …
TLR agonists as mediators of trained immunity: mechanistic insight and immunotherapeutic potential to combat infection
… are expressed in innate immune cells (ie dendritic cells, DCs; … (CPG) and the heterodimer
TLR7/TLR8, stimulated by single … viruses or self-RNAs released from damaged cells (86, 143). …
TLR7/TLR8, stimulated by single … viruses or self-RNAs released from damaged cells (86, 143). …
Optimization of plasmacytoid dendritic cell maturation for its development as cellular immunotherapeutic product
E Dimitriou - 2024 - oparu.uni-ulm.de
… Myeloid dendritic cells (mDCs) stem from the precursor DCs … -cells express the surface
marker CD4 and secrete cytokines … stem cell transplantation from CCR5 deficient donors to HIV-1…
marker CD4 and secrete cytokines … stem cell transplantation from CCR5 deficient donors to HIV-1…