… The glycolytic modulator TP53-Inducible Glycolysis and … of cancer and has a role in metabolic
rewiring during tumor … activation and regulating anabolic metabolic reprogramming in T …

… of TIGAR (TP53-inducible glycolysis and apoptosis regulator), a … glucose metabolism, to try
to identify the role that TIGAR play in … determinant of metabolic reprogramming in SCCHN. My …

… metabolism. In the second part of this thesis, we aimed to determine the mechanisms by
which TP53 inducible glycolysis and apoptosis regulator (TIGAR) promotes metabolic …

… the cancer cells to undergo metabolic reprogramming through … with p53 thereby regulating
key genes of the glycolytic and … of TIGAR, SCO2, TCF19, and p53 from the HCC tumor RNA- …

… of metabolic “TP53-inducible glycolysis and apoptosis regulator” (… in regulating the glycolytic
pathway through TIGAR and phosphoglycerate mutase (PGM) to suppress the glycolytic …

… The metabolic regulation is highly altered and is considered … TP53-induced glycolysis and
apoptosis regulator (TIGAR) … to metabolic reprogramming, cancer cells adopt glycolysis as …

… of TP53-inducible glycolysis and apoptosis regulator (TIGAR) … TIGAR expression since the
glucose metabolism of tumor … of p53, TIGAR is involved in the metabolic reprogramming of …

… So we hypothesize that the TIGAR is a key regulator of cancer … of TIGAR in solid tumors
inhibits ROS production. Besides, metabolic reprogramming, such as a shift in glycolysis and …

… TP53-inducible Glycolysis and Apoptosis Regulator (TIGAR) expression is positively regulated
(Bensaad et al. 2006). Also, p53 regulates basal expression of Apoptosis … of cancer cells, …

… The metabolic cross talk between CAFs and cancer cells involves, among others, Caveolin-…
κB), and TP53-induced glycolysis and apoptosis regulator (TIGAR). It has been observed that …