How TRPC channels modulate hippocampal function
R Gualdani, P Gailly - International journal of molecular sciences, 2020 - mdpi.com
… factor (BDNF) such as cerebellar granule neuron survival in response to BDNF [68], BDNF-…
3 and DAG [71] and specific cationic channels, which enhance excitability by depolarizing …
3 and DAG [71] and specific cationic channels, which enhance excitability by depolarizing …
Functional importance of transient receptor potential (TRP) channels in neurological disorders
… As mentioned above, TRPC channels are not only known to play an important role in
neuronal outgrowth and survival during brain development but are also believed to play a pivotal …
neuronal outgrowth and survival during brain development but are also believed to play a pivotal …
Roles of TRP channels in neurological diseases
R Wang, S Tu, J Zhang, A Shao - Oxidative Medicine and …, 2020 - Wiley Online Library
… , which is abundantly expressed in hippocampus and cerebellar neurons, is activated by …
Thus, TRPC6 expression in neurons plays a beneficial role for neuronal survival and can be …
Thus, TRPC6 expression in neurons plays a beneficial role for neuronal survival and can be …
Contribution of TRPC channels in neuronal excitotoxicity associated with neurodegenerative disease and ischemic stroke
… which TRPC channels are involved in neuronal survival or … mGluR1/5 is to enhance neuronal
excitability via a number of … is highly expressed in cerebellar Purkinje neurons and involved …
excitability via a number of … is highly expressed in cerebellar Purkinje neurons and involved …
Novel targets for stroke therapy: Special focus on TRPC channels and TRPC6
L Liu, L Gu, M Chen, Y Zheng, X Xiong… - Frontiers in Aging …, 2020 - frontiersin.org
… outgrowth and neuronal survival during normal … in cerebellar granule neurons. By contrast,
upregulation of TRPC3 or TRPC6 was shown to suppress neuronal apoptosis and promote …
upregulation of TRPC3 or TRPC6 was shown to suppress neuronal apoptosis and promote …
mGluR1 signaling in cerebellar Purkinje cells: Subcellular organization and involvement in cerebellar function and disease
… TRPC channels. Homer proteins are encoded by three genes (Homer1–3), and alternative
splicing of Homer1 generates long- and short-splice variants of Homer1a–c (Kato et al., 1998; …
splicing of Homer1 generates long- and short-splice variants of Homer1a–c (Kato et al., 1998; …
The role of TRP channels and PMCA in brain disorders: intracellular calcium and pH homeostasis
SM Hwang, JY Lee, CK Park, YH Kim - Frontiers in Cell and …, 2021 - frontiersin.org
… On the other hand, TRPC3 or TRPC6 promotes neurotrophin action on brain-derived
neurotrophic factor (BDNF) by improving neuronal survival through Ca 2+ influx (Huang et al., 2011)…
neurotrophic factor (BDNF) by improving neuronal survival through Ca 2+ influx (Huang et al., 2011)…
Target molecules of STIM proteins in the central nervous system
K Serwach, J Gruszczynska-Biegala - Frontiers in molecular …, 2020 - frontiersin.org
… other than Orai pathways, including TRPC channels, VGCCs, AMPA and … neuronal survival
in models of TBI, decreasing neuronal … promotes the degradation of Sp4 in cerebellar granule …
in models of TBI, decreasing neuronal … promotes the degradation of Sp4 in cerebellar granule …
Transient receptor potential-canonical channels in the nervous system
Y Tong, J Yang, L Du - 2023 - researchsquare.com
… In this paper, we review the role of TRPC channels in … cerebellar granule neuron cells,
TRPC3 and C6 promote BDNF-… , especially in neuronal differentiation, survival, and neurological …
TRPC3 and C6 promote BDNF-… , especially in neuronal differentiation, survival, and neurological …
Therapeutic potential of pharmacological agents targeting TRP channels in CNS disorders
… Inhibition of this TRPM4 channel promoted angiogenesis and improved vascular integrity …
enhancing TRP channel activity following stroke will increase the chance of neuronal survival (…
enhancing TRP channel activity following stroke will increase the chance of neuronal survival (…