Enzymatic Modulation of Tachykinins and VIP in the Lung

CM Lilly, SA Shore - Proinflammatory and Antiinflammatory …, 2020 - taylorfrancis.com
… Of the three recognized mammalian tachykinins, only substance P (SP) and neurokinin A
(NKA) have been identified in the lungs and airways. Tachykinins are neurotransmitters and …

Regulatory peptides in asthma

K Kaczyńska, D Zając, P Wojciechowski… - International Journal of …, 2021 - mdpi.com
Tachykinins are involved in a cough reflex and in the inflammatory response in the lungs,
as they were shown to be important mediators of the neurogenic inflammation in asthma, …

The immunomodulatory effects of tachykinins and their receptors

S Khorasani, N Boroumand, F Lavi Arab… - Journal of Cellular …, 2020 - Wiley Online Library
Tachykinins (TKs) are a family of neuropeptides mainly expressed by neuronal and non‐neuronal
cell types, especially immune cells. Expression of TKs receptors on immune cell …

The tachykinin family of peptides and their receptors

D Regoli, P Geppetti, G Caló - … and Antiinflammatory Peptides, 2020 - taylorfrancis.com
… , tachykinins may release histamine from lung mast cells via NK-1 receptor activation in Fisher
344 rats (51 ). Much evidence has been reported on the presence of tachykinintachykinin

Tachykinin antagonists in asthma and inflammation

CA Maggi - Proinflammatory and Antiinflammatory Peptides, 2020 - taylorfrancis.com
… Multiple tachykinin binding sites in peripheral tissues and in brain. Eur J Pharmacol 1986; …
Release of multiple tachykinins from capsaicin-sensitive sensory nerves in the lung by …

Transient receptor potential ankyrin-1 causes rapid bronchodilation via nonepithelial PGE2

BJ Marsh, AD Fryer, DB Jacoby… - … of Physiology-Lung …, 2020 - journals.physiology.org
… Investigations into TRPA1 function in the lungs have … via antidromic release of tachykinins
by TRPA1-positive sensory … the function of TRPA1 within the lungs, we sought to conclusively …

Pharmacological importance of TG12 from tachykinin and its toxicological behavior against multidrug-resistant bacteria Klebsiella pneumonia

SV Raju, P Sarkar, M Pasupuleti, NT Saraswathi… - … and Physiology Part C …, 2021 - Elsevier
tachykinin (Tac) protein of an established teleost Channa striatus (Cs) transcriptome.
TachykininTachykinin mRNA upregulated in C. striatus treated with Aeromonas hydrophila and …

Neurokinin 1 and 2 receptors are involved in PGE2-and citric acid-induced cough and ventilatory responses

J Zhuang, X Gao, L Zhao, W Wei, F Xu - Respiratory Physiology & …, 2022 - Elsevier
… After the exposure, the animals were euthanized and the lungs collected to detect … -neurons
labeled by TRPV1 or EP3 receptor co-expressed the tachykinin receptor (NK 1 R or NK 2 R). …

Antiinflammatory actions of VIP in the lungs and airways

SI Said - Proinflammatory and antiinflammatory peptides, 2020 - taylorfrancis.com
… was investigated in lungs from immunologically sensitized guinea … was investigated in lungs
from immunologically sensitized … In the same guinea pig lung model in which the lungs are …

Peptidergic systems and cancer: Focus on tachykinin and calcitonin/calcitonin gene-related peptide families

ML Sánchez, FD Rodríguez, R Coveñas - Cancers, 2023 - mdpi.com
… This review highlights the essential roles played by both tachykinin and calcitonin/calcitonin
gene-related peptide families in cancer progression, which support the application of …