[HTML][HTML] Targeted treatment of head and neck (pre) cancer: preclinical target identification and development of novel therapeutic applications

AM van Harten, RH Brakenhoff - Cancers, 2021 - mdpi.com
… , in the case of radiotherapy enhanced by image-guided planning and intensity modulation.
… lethality, which will expand our pre-clinical toolbox to uncover new HNSCC vulnerabilities in …

[HTML][HTML] Validation of fully automated robust multicriterial treatment planning for head and neck cancer impt

M Huiskes, W Kong, M Oud, K Crama, C Rasch… - … Journal of Radiation …, 2024 - Elsevier
… Our purpose was to compare robust intensity modulated proton therapy (IMPT) plans, … clinical
target volume [CTV]7000) and 5425 cGy dose prescription to the bilateral elective volumes (…

[图书][B] Intensity modulated radiation therapy: a clinical overview

IJ Das, NJ Sanfilippo, A Fogliata, L Cozzi - 2020 - iopscience.iop.org
… The main interests in her career have been mostly focused in the preclinical investigation
of … of lymph node target volumes in head and neck conformal radiotherapy. Proposal for …

[HTML][HTML] Pre-clinical validation of a novel system for fully-automated treatment planning

R Bijman, AW Sharfo, L Rossi, S Breedveld… - Radiotherapy and …, 2021 - Elsevier
… The clinical target volume (CTV) consisted of the GTV, expanded isotropically with a margin
of 1 … Parotid-sparing intensity modulated versus conventional radiotherapy in head and neck

Development and Validation of a Clinically Relevant Workflow for MR-Guided Volumetric Arc Therapy in a Rabbit Model of Head and Neck Cancer

E Rajab Bolookat, H Malhotra, LJ Rich, S Sexton… - Cancers, 2020 - mdpi.com
… The planned target volume (PTV) was defined as 0.5 cm expansion of the gross tumor …
conventional intensity modulated radiation therapy in advanced head and neck cancer. World J. …

Knowledge-based planning for robustly optimized intensity-modulated proton therapy of head and neck cancer patients

Y Xu, J Cyriac, M De Ornelas, E Bossart… - Frontiers in …, 2021 - frontiersin.org
Head and neck (HN) cancer therapy is both challenging and complicated due to the proximity
of clinical target volumes (CTVs) … Intensity-modulated radiation therapy (IMRT), volumetric …

Radiotherapy–immunotherapy combination: how will we bridge the gap between pre-clinical promise and effective clinical delivery?

E Romano, J Honeychurch, TM Illidge - Cancers, 2021 - mdpi.com
… field IMRT (intensity-modulated radiation therapy) may have … Initial pre-clinical studies have
demonstrated that DLNs are … excluding DLNs from the target volume of irradiation enhances …

Ultra-high dose rate transmission beam proton therapy for conventionally fractionated head and neck cancer: Treatment planning and dose rate distributions

P van Marlen, M Dahele, M Folkerts, E Abel… - Cancers, 2021 - mdpi.com
… require energy modulation, which lowers the beam intensity). Pre-clinical research dating …
were used with a boost planning target volume (PTVB, 36–209 cm 3 ) and elective planning …

[HTML][HTML] Quality of life and toxicity guided treatment plan optimisation for head and neck cancer

HP van der Laan, A van der Schaaf… - Radiotherapy and …, 2021 - Elsevier
… of intensity modulated radiation therapy (IMRT) introduced a paradigm shift in radiation
Planning target volumes (PTV) were restricted to 5 mm within the skin surface for the purpose of …

[HTML][HTML] Towards automated organs at risk and target volumes contouring: Defining precision radiation therapy in the modern era

D Jin, D Guo, J Ge, X Ye, L Lu - Journal of the National Cancer Center, 2022 - Elsevier
… In a subsequent dosimetric experiment, while fixing the original dose grid in a clinical intensity
modulated radiotherapy (IMRT) plan, the clinical reference OAR contours were replaced …