A review of techniques for biodelivery of nerve growth factor (NGF) to the brain in relation to Alzheimer's disease
… basal forebrain region (basal forebrain cholinergic neurons, BFCNs) but innervate wide areas
of the brain. … new tools for targeted delivery of neurotrophins to the brain, several important …
of the brain. … new tools for targeted delivery of neurotrophins to the brain, several important …
[HTML][HTML] Nerve growth factor-based therapy in Alzheimer's disease and age-related macular degeneration
G Amadoro, V Latina, BO Balzamino, R Squitti… - Frontiers in …, 2021 - frontiersin.org
… nerve growth factor (NGF) signaling, metabolism, and/or defect in NGF transport to the basal
forebrain cholinergic … EC-NGF biodelivery devices targeting the basal forebrain of implanted …
forebrain cholinergic … EC-NGF biodelivery devices targeting the basal forebrain of implanted …
[HTML][HTML] Synergic treatment of Alzheimer's disease with brain targeted nanoparticles incorporating NgR-siRNA and brain derived neurotrophic factor
Z Wang, Y Cheng, D Zhao, A Pliss, J Liu… - Smart Materials in …, 2020 - Elsevier
… brain-targeted modification, the nanoparticles overcome the blood-brain barrier were delivered
into the basal forebrain … action of central cholinergic neuronal regeneration, and BDNF …
into the basal forebrain … action of central cholinergic neuronal regeneration, and BDNF …
A Review of Techniques for Biodelivery of Nerve Growth Factor (NGF) to the Brain in Relation to AlzheimerTs
… in the basal forebrain region (basal forebrain cholinergic … tools for targeted delivery of
neurotrophins to the brain, several … of Alzheimer disease in basal forebrain cholinergic neurons: …
neurotrophins to the brain, several … of Alzheimer disease in basal forebrain cholinergic neurons: …
Gene and cell therapy for the nucleus basalis of Meynert with NGF in Alzheimer's disease
M Eriksdotter, S Mitra - Handbook of Clinical Neurology, 2021 - Elsevier
… of acetylcholine-esterase targeting the cholinergic system with … cholinergic system in AD
focusing on nerve growth factor (… is required for the survival and function of the basal forebrain …
focusing on nerve growth factor (… is required for the survival and function of the basal forebrain …
Nerve growth factor gene delivery across the blood–brain barrier to reduce beta amyloid accumulation in AD mice
BDS Rodrigues, T Kanekiyo, J Singh - Molecular Pharmaceutics, 2020 - ACS Publications
… nerve growth factor (NGF) gene using brain-targeted liposomal nanoparticles was investigated
for the treatment of Alzheimer’s disease … of basal forebrain cholinergic neurons. (5−7) It …
for the treatment of Alzheimer’s disease … of basal forebrain cholinergic neurons. (5−7) It …
Focused ultrasound delivery of a selective TrkA agonist rescues cholinergic function in a mouse model of Alzheimer's disease
K Xhima, K Markham-Coultes, H Nedev, S Heinen… - Science …, 2020 - science.org
… aging, nerve growth factor (NGF) enhances cholinergic cell … achieved noninvasive delivery
of D3 to the basal forebrain in … is an effective method for targeted drug delivery to the basal …
of D3 to the basal forebrain in … is an effective method for targeted drug delivery to the basal …
Nerve growth factor: Influence on cholinergic neurons in the CNS
C Eva - CNS Neurotransmitters and Neuromodulators, 2020 - taylorfrancis.com
… Target derived growth factors that regulate neuronal survival … factor for cholinergic neurons
located in basal forebrain and … of cholinergic neurons in the basal forebrain in Alzheimer’s …
located in basal forebrain and … of cholinergic neurons in the basal forebrain in Alzheimer’s …
[HTML][HTML] Peptides derived from growth factors to treat Alzheimer's disease
S Gascon, J Jann, C Langlois-Blais, M Plourde… - International Journal of …, 2021 - mdpi.com
… can target selective signaling pathways involved in neuron … dysregulation of the cholinergic
system in the basal forebrain, a … of neurotrophic factors (nerve growth factor (NGF) and brain-…
system in the basal forebrain, a … of neurotrophic factors (nerve growth factor (NGF) and brain-…
Postmortem analysis in a clinical trial of AAV2-NGF gene therapy for Alzheimer's disease identifies a need for improved vector delivery
MJ Castle, FC Baltanás, I Kovacs… - Human gene …, 2020 - liebertpub.com
… AAV2-NGF successfully engaged the target cholinergic neurons of the basal forebrain. In this
study, … by loss of cholinergic neurons in the basal forebrain. Nerve growth factor (NGF) is an …
study, … by loss of cholinergic neurons in the basal forebrain. Nerve growth factor (NGF) is an …