[HTML][HTML] Elevated levels of miR-144-3p induce cholinergic degeneration by impairing the maturation of NGF in Alzheimer's disease
LT Zhou, J Zhang, L Tan, HZ Huang, Y Zhou… - Frontiers in cell and …, 2021 - frontiersin.org
… Nerve growth factor (NGF) is secreted in brain regions that receive projections from the basal
forebrain cholinergic … degeneration in AD and identified a potential therapeutic target for AD…
forebrain cholinergic … degeneration in AD and identified a potential therapeutic target for AD…
[HTML][HTML] Brain-derived neurotrophic factor in Alzheimer's disease and its pharmaceutical potential
L Gao, Y Zhang, K Sterling, W Song - Translational neurodegeneration, 2022 - Springer
… of how BDNF genomic structure is connected to factors that regulate BDNF signaling. We
then discuss the role of BDNF in AD and the potential of BDNF-targeting therapeutics for AD. …
then discuss the role of BDNF in AD and the potential of BDNF-targeting therapeutics for AD. …
Nanoparticlized system: promising approach for the management of Alzheimer's disease through intranasal delivery
S Bahadur, N Sachan, RK Harwansh… - Current …, 2020 - ingentaconnect.com
… factors like insulin growth factors, nerve growth factors, … Further, AD linked with acetylcholine
and cholinergic neurons, … for drug delivery to brain, among them intranasal drug delivery …
and cholinergic neurons, … for drug delivery to brain, among them intranasal drug delivery …
[HTML][HTML] The involvement of insulin-like growth factor 1 and nerve growth factor in alzheimer's disease-like pathology and survival role of the mix of embryonic …
M Aghajanov, S Matinyan, V Chavushyan… - International Journal of …, 2021 - mdpi.com
… , we aimed to identify the involvement of neurotrophic factors—the insulin-like growth factor
1 (IGF-1) and nerve growth factor (… Selective degeneration of the nucleus basalis cholinergic …
1 (IGF-1) and nerve growth factor (… Selective degeneration of the nucleus basalis cholinergic …
[HTML][HTML] Increased endogenous GDNF in mice protects against age-related decline in neuronal cholinergic markers
… types of dementia, including Alzheimer’s disease (AD), Lewy … the level of nerve growth factor
(NGF), which is important for … significantly lower Cholinergic index in basal forebrain (about …
(NGF), which is important for … significantly lower Cholinergic index in basal forebrain (about …
Intranasal drug delivery for treatment of Alzheimer's disease
… of nervous impulses in the synapses cholinergic fibers by hydrolysis of acetylcholine (ACh) …
, or proteins (eg, insulin, human growth hormone, interferon) to improve their absorption and …
, or proteins (eg, insulin, human growth hormone, interferon) to improve their absorption and …
[HTML][HTML] Recent advances in the treatment of Alzheimer's disease using nanoparticle-based drug delivery systems
P Poudel, S Park - Pharmaceutics, 2022 - mdpi.com
… Cholinergic Deficit During the progression of AD, cholinergic neurons in the basal forebrain
… (Ru) as a carrier, which was loaded with nerve growth factor (NGF) and sealed with a phase …
… (Ru) as a carrier, which was loaded with nerve growth factor (NGF) and sealed with a phase …
Gene therapy in Alzheimer disease patients
M ERIKSDOTTER-JÖNHAGEN, B LINDEROTH… - Gene therapy - degruyter.com
… delivery of NGF to the cholinergic basal forebrain can arrest and even reverse the degeneration
of the basal forebrain cholinergic … and intracerebroventricular drug delivery by infusion …
of the basal forebrain cholinergic … and intracerebroventricular drug delivery by infusion …
Intravenous and non-invasive drug delivery to the mouse basal forebrain using MRI-guided focused ultrasound
… cholinergic-based therapies is not only the production of biologically active compounds but
also a platform for safe and efficient drug delivery to the basal forebrain… Alzheimer’s disease (…
also a platform for safe and efficient drug delivery to the basal forebrain… Alzheimer’s disease (…
The NGF metabolic pathway: New opportunities for biomarker research and drug target discovery: NGF pathway biomarkers and drug targets
R Pentz, MF Iulita - Recent Advances in NGF and Related Molecules: The …, 2021 - Springer
… mediator of Alzheimer’s disease (AD) symptoms, may play a disease-… of basal forebrain
cholinergic neurons in AD as the result of pathological alterations to nerve growth factor (NGF) …
cholinergic neurons in AD as the result of pathological alterations to nerve growth factor (NGF) …