… growth factor, and glial cell-derived neurotrophic factor. For … and then introduced into the
basal forebrain. Results showed a … these specific factors involved in cholinergic survival seems …

… Basal forebrain cholinergic neurons (BFCNs) extend long … of the immature proform of nerve
growth factor (proNGF) in the … disorders such as Alzheimer’s disease (AD) are associated …

… on the potential therapeutic role of targeting the cholinergic or the adrenergic system to …
that basal forebrain cholinergic neurons are uniquely reliant on Nerve Growth Factor (NGF) …

… ) including Parkinson's disease (PD), Alzheimer's disease (AD) … Large molecules such as
proteins and growth factors can … (TfR) is commonly used as target for drug delivery to the brain […

… as selective degeneration of cholinergic basal forebrain neurons. These … Our results also
revealed that the cholinergic … Therefore, targeting cholinergic function (through cholinesterase …

… platforms that may overcome the targeted delivery challenges for AD gene therapy. In …
Nerve growth factor (NGF) gene therapy, targeting the preservation of basal forebrain cholinergic …

… brain diseases including Alzheimer's disease, Parkinson's … systems such as adrenergic,
cholinergic and serotonergic. The … necrosis factor and membrane proteins and growth factors …

… and differentiation depend on nerve growth factor (NGF) and … of deep and early basal
forebrain cholinergic neurons (BFCN… the target tissues of the hippocampus and cortex, which is …

… , is also a nonspecific esterase that causes the cholinergic system in the basal forebrain to
… Over 30 years ago, the neurotrophin known as nerve growth factor (NGF) was suggested as …

… brain cholinergic system is the basal forebrain cholinergic system [23,26], and it is well
known that the basal forebrain cholinergic neurons (BFCN) depend on nerve growth factor (NGF) …