Dry powder aerosol containing muco-inert particles for excipient enhanced growth pulmonary drug delivery
… We conducted a proof-of-concept study using … using an excipient enhanced growth (EEG)
strategy, aiming to minimize extrathoracic airway loss, maximize deposition in the airway and …
strategy, aiming to minimize extrathoracic airway loss, maximize deposition in the airway and …
Excipient Enhanced Growth Aerosol Surfactant Replacement Therapy in an In Vivo Rat Lung Injury Model
FJ Kamga Gninzeko, MS Valentine, CK Tho… - … and Pulmonary Drug …, 2020 - liebertpub.com
… target the small airways. We have developed an excipient enhanced growth (EEG) powder
aerosol formulation … helps target the site of deposition and prevents exhalation of the …
aerosol formulation … helps target the site of deposition and prevents exhalation of the …
[HTML][HTML] Dual targeting powder formulation of antiviral agent for customizable nasal and lung deposition profile through single intranasal administration
… was used as the sole excipient to enhance drug solubility. With the … and lower airways for
the prevention and treatment of human … desirable aerosol deposition profile at the target sites. …
the prevention and treatment of human … desirable aerosol deposition profile at the target sites. …
Excipients for Novel Inhaled Dosage Forms: An Overview
… mouth, and following drug deposition in lung airways, has … enhance its absorption or deposition
in the target lung regions, … concentration to produce homogeneous aerosol droplets [46]. …
in the target lung regions, … concentration to produce homogeneous aerosol droplets [46]. …
Regional deposition: targeting
AR Martin - Journal of aerosol medicine and pulmonary drug …, 2021 - liebertpub.com
… The aim is straightforward: to increase the therapeutic effect of the drug at its targeted … is
the predominant mechanism of aerosol deposition in the upper and central airways; therefore, …
the predominant mechanism of aerosol deposition in the upper and central airways; therefore, …
Respiratory tract: structure and attractions for drug delivery using dry powder inhalers
NA ElKasabgy, IM Adel, MF Elmeligy - AAPS PharmSciTech, 2020 - Springer
… Respiratory tract can be divided into upper airways, central … ,14,15): (a) a more targeted drug
delivery to the lungs in high … drug with or without other excipients for example together with …
delivery to the lungs in high … drug with or without other excipients for example together with …
[HTML][HTML] Aerosol pulmonary immune engineering
ER Sudduth, M Trautmann-Rodriguez, N Gill… - Advanced Drug Delivery …, 2023 - Elsevier
… of complexing these materials into drug delivery vehicles for enhanced release outcomes. …
key immune targets, fundamentals of aerosol drug delivery, and preclinical pulmonary models …
key immune targets, fundamentals of aerosol drug delivery, and preclinical pulmonary models …
Recent developments in dry powder inhalation (DPI) formulations for lung-targeted drug delivery
… the development and approval of new inhalable excipients is … spread of respiratory viruses,
airway inflammatory conditions… as a pharmaceutical excipient as a carrier for aerosol delivery. …
airway inflammatory conditions… as a pharmaceutical excipient as a carrier for aerosol delivery. …
Patented therapeutic drug delivery strategies for targeting pulmonary diseases
… target sites may get deposited in the numerous airway … may grow in size as they pass
through the humid airway, … The use of aerosol inhalers for respiratory conditions dates back to …
through the humid airway, … The use of aerosol inhalers for respiratory conditions dates back to …
[HTML][HTML] Contemporary formulation development for inhaled pharmaceuticals
T Sou, CAS Bergström - Journal of Pharmaceutical Sciences, 2021 - Elsevier
… For respiratory conditions, targeted drug delivery directly to … of the lung lining fluid differ at
various parts of the airways and … number of excipients have been approved for pulmonary use (…
various parts of the airways and … number of excipients have been approved for pulmonary use (…