Inflammation, oxidative stress, senescence in atherosclerosis: thioredoxine-1 as an emerging therapeutic target

K El Hadri, R Smith, E Duplus, C El Amri - International journal of …, 2021 - mdpi.com
… of the impact of inflammation, oxidative stress, and senescence in atherosclerosis; and the
… In this review, we place particular emphasis on the thioredoxin system by providing updated …

Therapeutic strategies targeting inflammation and immunity in atherosclerosis: how to proceed?

SE Engelen, AJB Robinson, YX Zurke… - Nature Reviews …, 2022 - nature.com
… the therapeutic potential of targeting the immune system in atherosclerosis. First, we provide
… ongoing clinical trials targeting the immune system in atherosclerosis and identify important …

Oxidative stress and antioxidants in atherosclerosis development and treatment

AV Poznyak, AV Grechko, VA Orekhova… - Biology, 2020 - mdpi.com
… during inflammation, sepsis and oxidative stressfocus is shifted from systemic antioxidants,
such as vitamins C and E to more targeted therapies that can tackle local oxidative stress at …

The role of oxidative stress in atherosclerosis

M Batty, MR Bennett, E Yu - Cells, 2022 - mdpi.com
… that can target multiple aspects of atherosclerosis. We … of ROS in atherosclerosis, the
consequences of oxidative stress, and … Endothelial oxidative stress therefore promotes …

Anti-inflammatory therapy for atherosclerosis: focusing on cytokines

AV Poznyak, D Bharadwaj, G Prasad… - International journal of …, 2021 - mdpi.com
… lipid metabolism alterations, oxidative stress, and inflammation. … atherosclerosis as well. In
this review, we summarized data on targeting the most studied inflammatory molecular targets

Inflammation and atherosclerosis: signaling pathways and therapeutic intervention

P Kong, ZY Cui, XF Huang, DD Zhang… - … and targeted therapy, 2022 - nature.com
… Despite protecting against vascular inflammation and oxidative stress, accumulation of
SM22α protein accelerates senescence of VSMCs and vascular aging via suppression of murine …

Management of oxidative stress and inflammation in cardiovascular diseases: mechanisms and challenges

T Donia, A Khamis - Environmental Science and Pollution Research, 2021 - Springer
… in the onset and development of atherosclerotic plaques. In this … focus on the laboratory
biomarkers and physiological tests for the evaluation of oxidative stress status and inflammatory

[HTML][HTML] Focus: the science of stress: oxidative stress and inflammation in cardiovascular diseases and cancer: role of non-coding RNAs

P Ginckels, P Holvoet - The Yale Journal of Biology and Medicine, 2022 - ncbi.nlm.nih.gov
target several miRs, causing even opposite effects on stress conditions. Oxidative Stress
and Inflammation Within Atherosclerosis Figure 1 illustrates the mechanisms in atherosclerosis

Inflammation, oxidative stress, vascular aging and atherosclerotic ischemic stroke

IK Koutsaliaris, IC Moschonas… - Current Medicinal …, 2022 - ingentaconnect.com
… for atherosclerotic ischemic stroke. The aim of the present review is to present the role …
oxidative stress and inflammation in vascular aging, as well as their involvement in atherosclerotic

Targeting oxidative stress in disease: Promise and limitations of antioxidant therapy

HJ Forman, H Zhang - Nature Reviews Drug Discovery, 2021 - nature.com
… We focus on current understanding of the mechanisms … , and in atherosclerosis); second,
oxidative stress as the … common features of inflammation and oxidative stress with SIRS …