Pyroptosis is a critical immune-inflammatory response involved in atherosclerosis

X He, X Fan, B Bai, N Lu, S Zhang, L Zhang - Pharmacological Research, 2021 - Elsevier
… In this review, we focus on the pathogenesis, influence, and … and noteworthy method for
targeted therapy of pyroptosis in AS. … oxidative stress and inflammation. Byon et al. showed that …

Myeloperoxidase: a potential therapeutic target for coronary artery disease

T Chaikijurajai, WHW Tang - Expert opinion on therapeutic targets, 2020 - Taylor & Francis
… with lower inflammation, vascular oxidative stress, and atheroscleroticinflammation in CAD
has been increasingly recognized, and recent research focused on discovering novel targets

Oxidative stress in cardiac hypertrophy: From molecular mechanisms to novel therapeutic targets

CJA Ramachandra, S Cong, X Chan, EP Yap… - Free Radical Biology …, 2021 - Elsevier
… Though NOX2 and NOX4 have been the main focus of oxidative stress, recent evidence … it
would seem that not only does inflammation induce oxidative stress but the reverse is also true…

[HTML][HTML] Dietary patterns and biomarkers of oxidative stress and inflammation: A systematic review of observational and intervention studies

K Aleksandrova, L Koelman, CE Rodrigues - Redox biology, 2021 - Elsevier
Oxidative stress and inflammation are known to play a critical role in ageing and chronic
disease development and could therefore represent important targets … A primarily focus was put …

Targeting oxidative stress and anti-oxidant defence in diabetic kidney disease

JA Østergaard, ME Cooper, KAM Jandeleit-Dahm - Journal of nephrology, 2020 - Springer
… patients despite a clinical focus on risk factor modification … atherosclerosis development
in a diabetic atherosclerosis … both anti-inflammatory and oxidative stress lowering effects, …

Oxidative stress and vascular dysfunction in the retina: Therapeutic strategies

Y Ruan, S Jiang, A Musayeva, A Gericke - Antioxidants, 2020 - mdpi.com
… diseases targeting retinal signaling pathways involving ROS. … and death, tissue damage
and inflammatory responses, thus … on oxidative stress in the retina with a special focus on …

Recent advances in targeted stimuli-responsive nano-based drug delivery systems combating atherosclerosis

Y Song, H Jing, LB Vong, J Wang, N Li - Chinese Chemical Letters, 2022 - Elsevier
focus on the recent advances in stimuli-responsive NDDSs for AS therapy, including internal
stimuli (ROS, enzyme, shear stress… of pro-inflammatory macrophages and oxidative stress is …

Lipid peroxidation in atherosclerotic cardiovascular diseases

E Gianazza, M Brioschi… - Antioxidants & redox …, 2021 - liebertpub.com
… for ACVDs targeting oxidative stress producers or … oxidative stress and inflammation are
strictly related to the instability of atherosclerotic plaque, and the measurement of oxidative

[HTML][HTML] New perspectives on the therapeutic potential of quercetin in non-communicable diseases: Targeting Nrf2 to counteract oxidative stress and inflammation

L Zhang, LY Xu, F Tang, D Liu, XL Zhao… - Journal of …, 2024 - Elsevier
… In addition, we focused on the challenges and prospects for its clinical use. Que represents
… , and atherosclerosis. Nrf2 is critical to combating these diseases due to its antioxidative, anti-…

RIPK1 Expression Associates With Inflammation in Early Atherosclerosis in Humans and Can Be Therapeutically Silenced to Reduce NF-κB Activation and …

D Karunakaran, MA Nguyen, M Geoffrion, D Vreeken… - Circulation, 2021 - Am Heart Assoc
… inflammasome-independent and oxidative stress–dependent IL… is renewed focus in finding
novel therapeutic targets that act … targeting RIPK1 may be better suited to reduce inflammation